EP 1392836 A2 20040303 - SPECIFIC PROMOTOR OF THE HUMAN VASCULAR ENDOTHELIAL CADHERIN-2 (HVE-CAD-2) GENE AND THE THERAPEUTIC USES THEREOF
Title (en)
SPECIFIC PROMOTOR OF THE HUMAN VASCULAR ENDOTHELIAL CADHERIN-2 (HVE-CAD-2) GENE AND THE THERAPEUTIC USES THEREOF
Title (de)
GEFÄSSENDOTHEL-SPEZIFISCHER PROMOTOR DES HUMANEN VASCULAR ENDOTHELIAL CADHERIN-2 (HVE-CAD-2) GENS UND SEINE THERAPEUTISCHEN VERWENDUNGEN
Title (fr)
PROMOTEUR SPECIFIQUE DE L'ENDOTHELIUM VASCULAIRE DU GENE CADHERIN-2 (HVE-CAD-2) DE L'ENDOTHELIUM VASCULAIRE HUMAIN ET SES UTILISATIONS THERAPEUTIQUES
Publication
Application
Priority
- EP 0113321 W 20011116
- US 24939000 P 20001116
Abstract (en)
[origin: WO0240692A2] The invention relates to a nucleic acid fragment which contains the regulatory sequence of the VE-Cad-2- gene, a complete or a functional active variation thereof. The invention also relates to a nucleic acid construct containing the nucleic acid fragment and a functional nucleic acid sequence or a heterological gene, a vector or a vector system, a cell or a cell line, a transgenic non-human animal, a medicament, a diagnostic, an array, a method for identifying pharmaceutically active substances, a method for identifying functionally active variants, a method for isolating endothelium cells from stem cells, a method for treatment, a method for administering a medicament, the use of the nucleic acid fragment, the nucleic acid construct, the transformed cell or cell lines of the tests and the arrays.
IPC 1-7
C12N 15/85; C12N 15/11; C12Q 1/68; C12N 5/16; A61K 48/00; A61P 9/00; A01K 67/00
IPC 8 full level
A61P 9/00 (2006.01); C07K 14/705 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); C07K 14/70596 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A61K 2039/53 (2013.01)
Citation (search report)
See references of WO 0240692A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0240692 A2 20020523; WO 0240692 A3 20021114; AU 2071102 A 20020527; CA 2429317 A1 20020523; EP 1392836 A2 20040303; IL 155907 A0 20031223
DOCDB simple family (application)
EP 0113321 W 20011116; AU 2071102 A 20011116; CA 2429317 A 20011116; EP 01996615 A 20011116; IL 15590701 A 20011116