EP 1399455 A2 20040324 - NOVEL TRICYCLIC DIHYDRO-QUINOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
Title (en)
NOVEL TRICYCLIC DIHYDRO-QUINOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
Title (de)
TRIZYKLISCHE DIHYDROCHINOLINDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN DIE DIESE ENTHALTEN
Title (fr)
DERIVES TRICYCLIQUES DE DIHYDROQUINOLEINES,LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Publication
Application
Priority
- FR 0201716 W 20020522
- FR 0106791 A 20010523
Abstract (en)
[origin: WO02094840A2] The invention concerns a compound of formula (I), wherein: (a) represents a single or double bond; (b) represents a cycle selected among (i), (ii), (iii), (iv) and (v); R9a, R9b, R9c, X and Y are such as defined in the description; R1 represents a group selected among hydrogen, aryl, heteroaryl, cycloalkyl, alkyl optionally substituted, and COR11, wherein R11 is such as defined in the description; R2 to R8 represent each a group selected among hydrogen, halogen, hydroxy, polyhalogenoalkyl, nitro, alkyl optionally substituted, amino optionally substituted, alkoxy optionally substituted, -OPO(OH)2 and (II), wherein m represents an integer such that 1 </= m </= 4, or R2 with R3, or R3 with R4, or R4 with R5 together form with the carbon atoms which bear them a monocyclic or bicyclic group optionally containing 1 or 2 heteroatoms and optionally substituted; R16 represents a hydrogen atom or an alkyl group; (c) represents an aryl, heteroaryl or arylalkyl group; as well as its optical isomers, its addition salts to a pharmaceutically acceptable acid or base as well as its hydrates and solvates. The invention is useful for preparing medicines.
IPC 1-7
IPC 8 full level
A61K 31/4741 (2006.01); A61K 31/4743 (2006.01); A61K 31/4745 (2006.01); A61K 31/661 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 491/04 (2006.01); C07D 491/048 (2006.01); C07D 491/056 (2006.01); C07D 491/14 (2006.01); C07D 497/04 (2006.01); C07F 9/60 (2006.01); C07F 9/6561 (2006.01)
CPC (source: EP KR US)
A61P 35/00 (2018.01 - EP); C07D 491/04 (2013.01 - EP US); C07D 491/048 (2013.01 - KR); C07D 491/14 (2013.01 - EP US); C07F 9/6561 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02094840 A2 20021128; WO 02094840 A3 20030501; AR 033914 A1 20040107; BR 0209963 A 20040413; CA 2448197 A1 20021128; CN 1511161 A 20040707; CZ 20033496 A3 20040414; EA 200301172 A1 20040429; EP 1399455 A2 20040324; FR 2825092 A1 20021129; FR 2825092 B1 20050114; HU P0401345 A2 20041129; HU P0401345 A3 20061128; JP 2004529191 A 20040924; KR 20040008190 A 20040128; MX PA03010597 A 20040309; NO 20035214 D0 20031124; NO 20035214 L 20031124; PL 364083 A1 20041213; SK 16012003 A3 20040608; US 2004180917 A1 20040916; ZA 200308628 B 20041105
DOCDB simple family (application)
FR 0201716 W 20020522; AR P020101905 A 20020523; BR 0209963 A 20020522; CA 2448197 A 20020522; CN 02810348 A 20020522; CZ 20033496 A 20020522; EA 200301172 A 20020522; EP 02735551 A 20020522; FR 0106791 A 20010523; HU P0401345 A 20020522; JP 2002591513 A 20020522; KR 20037015307 A 20031122; MX PA03010597 A 20020522; NO 20035214 A 20031124; PL 36408302 A 20020522; SK 16012003 A 20020522; US 47724403 A 20031110; ZA 200308628 A 20031105