EP 1399545 A2 20040324 - METHOD FOR DETECTING CALPAIN 3 ACTIVITY IN A BIOLOGICAL SAMPLE AND PEPTIDES FOR IMPLEMENTING SAID METHOD

Title (en)

METHOD FOR DETECTING CALPAIN 3 ACTIVITY IN A BIOLOGICAL SAMPLE AND PEPTIDES FOR IMPLEMENTING SAID METHOD

Title (de)

METHODE ZUR DETEKTION DER AKTIVITÄT VON CALPAIN IN EINEM MUSTER UND PEPTIDE DAFÜR

Title (fr)

METHODE DE DETECTION DE L'ACTIVITE DE LA CALPAINE 3 DANS UN ECHANTILLON BIOLOGIQUE ET PEPTIDES POUR LA MISE EN OEUVRE DE LADITE MEHTODE

Publication

EP 1399545 A2 20040324 (FR)

Application

EP 02755089 A 20020624

Priority

FR 0202178 W 20020624
FR 0108614 A 20010629

Abstract (en)

[origin: FR2826656A1] The invention concerns a peptide coupled to at least a fluorogenic or colorogenic reporter molecule, characterised in that it contains at least a sequence of amino acids capable of being cleaved by calpain 3. The invention also concerns a method for detecting in vitro calpain 3 activity in a biological sample.

IPC 1-7

C12N 9/64; C12N 15/57; C12N 15/63; G01N 33/68; C12N 1/21

IPC 8 full level

G01N 33/50 (2006.01); C07K 4/00 (2006.01); C07K 7/00 (2006.01); C07K 19/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/64 (2006.01); C12N 15/09 (2006.01); C12N 15/57 (2006.01); C12Q 1/02 (2006.01); G01N 21/78 (2006.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01)

CPC (source: EP US)

C12N 9/6472 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US)

Citation (search report)

See references of WO 03002730A2

Citation (examination)

SORIMACHI H. ET AL: "Molecular Cloning of a Novel Mammalian Calcium-dependent Protease Distinct form Both m- and µ-Types", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, no. 25, 25 November 1989 (1989-11-25), pages 20106 - 20111, XP002010549

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

FR 2826656 A1 20030103; FR 2826656 B1 20030912; AU 2002321389 B2 20050324; CA 2429429 A1 20030109; CN 1514878 A 20040721; EP 1399545 A2 20040324; JP 2004520850 A 20040715; US 2004180395 A1 20040916; WO 03002730 A2 20030109; WO 03002730 A3 20031211

DOCDB simple family (application)

FR 0108614 A 20010629; AU 2002321389 A 20020624; CA 2429429 A 20020624; CN 02805730 A 20020624; EP 02755089 A 20020624; FR 0202178 W 20020624; JP 2003509092 A 20020624; US 43268803 A 20030527