Global Patent Index - EP 1406930 A4

EP 1406930 A4 20070110 - ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF

Title (en)

ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF

Title (de)

"ISOLIERTE MOLEKÜLE MIT SULFATIERTE GRUPPIERUNGEN ENTHALTENDEN EPITOPEN, ANTIKÖRPER GEGEN SOLCHE EPITOPE UND VERWENDUNGEN DAVON"

Title (fr)

MOLECULES ISOLEES RENFERMANT DES EPITOPES A FRACTIONS SULFATEES, ANTICORPS VIS-A-VIS DE CES EPITOPES, ET UTILISATIONS CORRESPONDANTES

Publication

EP 1406930 A4 20070110 (EN)

Application

EP 01994330 A 20011231

Priority

  • US 0149442 W 20011231
  • US 75118100 A 20001229
  • US 25894800 P 20001229

Abstract (en)

[origin: WO02053700A2] The present invention provides epitopes present on cancer cells and important in physiological phenomena such as cell rolling, metastasis, and inflammation. Therapeutic and diagnostic methods and compositions using antibodies capable of binding to the epitopes are provided. Methods and compositions according to the present invention can be used in diagnosis of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease.

IPC 1-7

C07K 16/00

IPC 8 full level

A61K 31/353 (2006.01); C12N 15/09 (2006.01); A61K 31/42 (2006.01); A61K 31/4709 (2006.01); A61K 31/522 (2006.01); A61K 31/5575 (2006.01); A61K 31/616 (2006.01); A61K 31/675 (2006.01); A61K 31/7072 (2006.01); A61K 31/711 (2006.01); A61K 31/727 (2006.01); A61K 31/728 (2006.01); A61K 35/12 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 51/00 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01); A61P 37/02 (2006.01); C07K 2/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01)

CPC (source: EP KR)

A61P 7/02 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/02 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61P 37/02 (2018.01 - EP); C07K 14/472 (2013.01 - EP); C07K 16/18 (2013.01 - KR); C07K 16/3061 (2013.01 - EP); A61K 38/00 (2013.01 - EP); C07K 2317/565 (2013.01 - EP); C07K 2317/622 (2013.01 - EP)

Citation (search report)

  • [X] WO 9812318 A1 19980326 - WISCONSIN ALUMNI RES FOUND [US]
  • [X] WO 9700079 A1 19970103 - GEN HOSPITAL CORP [US]
  • [X] WO 9965712 A2 19991223 - CUMMINGS RICHARD D [US], et al
  • [X] WO 9706176 A2 19970220 - UNIV OKLAHOMA [US], et al
  • [X] WO 9311778 A1 19930624 - SCRIPPS RESEARCH INST [US]
  • [X] LENGWEILER STEPHAN ET AL: "Preparation of monoclonal antibodies to murine platelet glycoprotein IIb/IIIa (alphaIIbbeta3) and other proteins from hamster-mouse interspecies hybridomas", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 262, no. 1, 19 August 1999 (1999-08-19), pages 167 - 173, XP002386677, ISSN: 0006-291X
  • [PX] JIROUSKOVA MARKETA ET AL: "A hamster antibody to the mouse fibrinogen gamma chain inhibits platelet-fibrinogen interactions and FXIIIa-mediated fibrin cross-linking, and facilitates thrombolysis", THROMBOSIS AND HAEMOSTASIS, vol. 86, no. 4, October 2001 (2001-10-01), pages 1047 - 1056, XP009068292, ISSN: 0340-6245
  • [T] JIROUSKOVA MARKETA ET AL: "Antibody blockade or mutation of the fibrinogen gamma-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen.", BLOOD, vol. 103, no. 6, 15 March 2004 (2004-03-15), pages 1995 - 2002, XP002386678, ISSN: 0006-4971
  • [T] SCHEINER T ET AL: "A monoclonal antibody to the fibrinogen gamma-chain alters fibrin clot structure and its properties by producing short, thin fibers arranged in bundles.", JOURNAL OF THROMBOSIS AND HAEMOSTASIS : JTH. DEC 2003, vol. 1, no. 12, December 2003 (2003-12-01), pages 2594 - 2602, XP009068271, ISSN: 1538-7933

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 02053700 A2 20020711; WO 02053700 A3 20040212; BR 0116764 A 20070109; CA 2433225 A1 20020711; CN 100347194 C 20071107; CN 1649900 A 20050803; CZ 20031982 A3 20040915; EP 1406930 A2 20040414; EP 1406930 A4 20070110; HU P0700079 A2 20070502; IL 156689 A0 20040104; JP 2005503756 A 20050210; KR 20030091953 A 20031203; MX PA03005945 A 20041015; PL 366223 A1 20050124; RU 2003123101 A 20050310

DOCDB simple family (application)

US 0149442 W 20011231; BR 0116764 A 20011231; CA 2433225 A 20011231; CN 01822884 A 20011231; CZ 20031982 A 20011231; EP 01994330 A 20011231; HU P0700079 A 20011231; IL 15668901 A 20011231; JP 2002555211 A 20011231; KR 20037008890 A 20030630; MX PA03005945 A 20011231; PL 36622301 A 20011231; RU 2003123101 A 20011231