EP 1409719 A1 20040421 - METHOD FOR DETECTING KNOWN MUTATIONS IN TUBE
Title (en)
METHOD FOR DETECTING KNOWN MUTATIONS IN TUBE
Title (de)
VERFAHREN ZUM NACHWEIS VON GEKANTEN POLYMORPHISMEN
Title (fr)
PROCEDE DE DETECTION DE MUTATIONS CONNUES EN TUBE
Publication
Application
Priority
- FR 0102574 W 20010808
- FR 0010425 A 20000808
Abstract (en)
[origin: WO0212557A1] The invention concerns a method for detecting a mutation in a target nucleic acid comprising amplification of the target DNA, specific hybridization of a probe with the DNA target, extension of the probe by selective addition of alpha S-phosphothioatedesoxynucleotide complementary of the mutation in a tube A and adding an alpha S-phosphothioatedesoxynucleotide complementary of the natural base corresponding to said mutation in a tube B; the resulting extended probe being resistant to digestion by an exonuclease, particularly by exonuclease III.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6827 (2018.01)
CPC (source: EP US)
C12Q 1/6827 (2013.01 - EP US)
C-Set (source: EP US)
Citation (search report)
See references of WO 0212557A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 0212557 A1 20020214; AU 8412101 A 20020218; EP 1409719 A1 20040421; FR 2812885 A1 20020215; US 2004076969 A1 20040422
DOCDB simple family (application)
FR 0102574 W 20010808; AU 8412101 A 20010808; EP 01963075 A 20010808; FR 0010425 A 20000808; US 34409303 A 20030808