EP 1412360 A4 20040707 - COMBINATION THERAPY OF AN SODm AND A CORTICOSTEROID FOR PREVENTION AND/OR TREATMENT OF INFLAMMATORY DISEASE

Title (en)

COMBINATION THERAPY OF AN SODm AND A CORTICOSTEROID FOR PREVENTION AND/OR TREATMENT OF INFLAMMATORY DISEASE

Title (de)

KOMBINATIONSTHERAPIE MIT EINEM SODm UND EINEM KORTIKOSTEROID ZUR PRÄVENTION UND/ODER BEHANDLUNG VON ENTZÜNDLICHEN ERKRANKUNGEN

Title (fr)

THERAPIE DE COMBINAISON D'UN MIMETIQUE D'ENZYME SUPEROXYDE-DISMUTASE (SODM) ET D'UN CORTICOSTEROIDE DESTINEE A LA PREVENTION ET/OU AU TRAITEMENT DE MALADIE INFLAMMATOIRE

Publication

EP 1412360 A4 20040707 (EN)

Application

EP 02752107 A 20020626

Priority

US 0220476 W 20020626
US 30108001 P 20010626

Abstract (en)

[origin: WO03000696A1] The present invention relates to pharmaceutical compositions and methods using such compositions for the treatment of inflammatory disease. Such compositions contain a catalyst for the dismutation of superoxide, including superoxide dismutase enzyme (SOD) and low molecular weight organic ligand derived metal complexes characterized in having the following structure: (Z)n that function as mimics of the enzyme (SOD mimetics or SODm) in combination with corticosteroids.

IPC 1-7

C07D 487/22; A61K 31/675; A61K 47/16

IPC 8 full level

C07D 487/22 (2006.01); A61K 31/00 (2006.01); A61K 31/555 (2006.01); A61K 31/57 (2006.01); A61K 31/573 (2006.01); A61K 31/675 (2006.01); A61K 45/00 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); C07D 471/08 (2006.01); C07J 5/00 (2006.01); C07J 7/00 (2006.01); C07J 71/00 (2006.01)

CPC (source: EP US)

A61K 31/00 (2013.01 - EP US); A61K 31/573 (2013.01 - EP US); A61K 31/675 (2013.01 - EP US); A61P 19/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP)

C-Set (source: EP US)

Citation (search report)

[Y] US 4252797 A 19810224 - ROSENTHAL WALTER
[Y] D. SALVEMINI ET AL: "Nopeptidyl mimetics of superoxide dismutase in clinical therapies for diseases", CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 57, no. 11, 2000, pages 1489 - 1492, XP002279224
[AD] SALVEMINI D ET AL: "A NONPEPTIDYL MIMIC OF SUPEROXIDE DISMUTASE WITH THERAPEUTIC ACTIVITY IN RATS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 286, 8 October 1999 (1999-10-08), pages 304 - 306, XP000971099, ISSN: 0036-8075
See references of WO 03000696A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 03000696 A1 20030103; CA 2451602 A1 20030103; EP 1412360 A1 20040428; EP 1412360 A4 20040707; JP 2005519852 A 20050707; MX PA03011795 A 20051018; US 2004266742 A1 20041230; US 2006035876 A1 20060216

DOCDB simple family (application)

US 0220476 W 20020626; CA 2451602 A 20020626; EP 02752107 A 20020626; JP 2003507099 A 20020626; MX PA03011795 A 20020626; US 14155005 A 20050531; US 48139604 A 20040602