Global Patent Index - EP 1414490 A1

EP 1414490 A1 20040506 - IMMUNOMODULATORY OLIGONUCLEOTIDE FORMULATIONS AND METHODS FOR USE THEREOF

Title (en)

IMMUNOMODULATORY OLIGONUCLEOTIDE FORMULATIONS AND METHODS FOR USE THEREOF

Title (de)

IMMUNMODULATORISCHE ZUSAMMENSETZUNGEN UND VERFAHREN ZUR IHRE ANWENDUNG

Title (fr)

PREPARATIONS D'OLIGONUCLEOTIDES IMMUNOMODULATEURS ET LEURS PROCEDES D'UTILISATION

Publication

EP 1414490 A1 20040506 (EN)

Application

EP 01959743 A 20010813

Priority

  • US 0125364 W 20010813
  • US 92742201 A 20010810
  • US 92788401 A 20010810

Abstract (en)

[origin: WO03015816A1] The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently bound, and feature a heptameric oligonucleotide, comprising at least one 5'-CG-3' sequence, bound to a microcarrier or nanocarrier.

IPC 1-7

A61K 39/39

IPC 8 full level

A61K 9/16 (2006.01); A61K 39/12 (2006.01); A61K 39/35 (2006.01); A61K 39/39 (2006.01); A61P 31/12 (2006.01); A61P 37/08 (2006.01); C12N 15/11 (2006.01); C12N 15/117 (2010.01); A61K 9/00 (2006.01)

CPC (source: EP)

A61K 9/1647 (2013.01); A61K 39/39 (2013.01); A61P 31/12 (2017.12); A61P 37/08 (2017.12); C12N 15/117 (2013.01); A61K 9/1617 (2013.01); A61K 9/167 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); C12N 2310/17 (2013.01); C12N 2310/315 (2013.01); C12N 2320/32 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

See references of WO 03015816A1

Citation (examination)

  • MANZEL L. ET AL: "LACK OF IMMUNE STIMULATION BY IMMOBILIZED CPG-OLIGODEOXYNUCLEOTIDE", ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, vol. 9, no. 5, October 1999 (1999-10-01), MARY ANN LIEBERT, INC., NEW YORK, US, pages 459 - 464, XP000946491
  • FEARON K. ET AL: "A minimal human immunomodulatory CpG motif that potently induces IFN-gamma and IFN-alpha production", EUR. J. IMMUNOL., vol. 33, 2003, pages 2114 - 2122

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 03015816 A1 20030227; AU 2001281267 B2 20080515; CA 2456201 A1 20030227; EP 1414490 A1 20040506; JP 2005510462 A 20050421

DOCDB simple family (application)

US 0125364 W 20010813; AU 2001281267 A 20010813; CA 2456201 A 20010813; EP 01959743 A 20010813; JP 2003520774 A 20010813