EP 1419269 A2 20040519 - METHODS FOR THE IDENTIFICATION OF INHIBITORS OF FLAVANONE 3-HYDROXYLASE EXPRESSION OR ACTIVITY IN PLANTS
Title (en)
METHODS FOR THE IDENTIFICATION OF INHIBITORS OF FLAVANONE 3-HYDROXYLASE EXPRESSION OR ACTIVITY IN PLANTS
Title (de)
VERFAHREN ZUR IDENTIFIZIERUNG VON INHIBITOREN DER FLAVANON-3-HYDROXYLASE-EXPRESSION ODER -AKTIVITÄT IN PFLANZEN
Title (fr)
PROCEDES PERMETTANT D'IDENTIFIER LES INHIBITEURS DE L'EXPRESSION OU DE L'ACTIVITE DE LA FLAVANONE-3HYDROXYLASE DANS DES PLANTES
Publication
Application
Priority
- US 0214694 W 20020508
- US 28949201 P 20010508
Abstract (en)
[origin: WO02090598A2] The present inventors have discovered that Flavanone 3-hydroxylase ("FHT") is essential for plant growth. Specifically, the inhibition of FHT gene expression in plant seedling results in small and chlorotic seedlings. Thus, FHT can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit FHT expression or activity. The present invention can be used to identify compounds having herbicide activity by contacting a compound with FHT and detecting the presence and/or absence of binding between the compound and the FHT, or alternatively, detecting a decrease in FHT expression or activity.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6895 (2018.01)
CPC (source: EP)
C12Q 1/6895 (2013.01); C12Q 2600/158 (2013.01)
Citation (search report)
See references of WO 02090598A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02090598 A2 20021114; WO 02090598 A3 20040325; EP 1419269 A2 20040519
DOCDB simple family (application)
US 0214694 W 20020508; EP 02726854 A 20020508