Global Patent Index - EP 1423122 A4

EP 1423122 A4 20081210 - COMPOSITIONS AND METHODS RELATING TO NOVEL BENZODIAZEPINE COMPOUNDS AND TARGETS THEREOF

Title (en)

COMPOSITIONS AND METHODS RELATING TO NOVEL BENZODIAZEPINE COMPOUNDS AND TARGETS THEREOF

Title (de)

ZUSAMMENSETZUNGEN UND VERFAHREN IN VERBINDUNG MIT NEUEN BENZODIAZEPIN-VERBINDUNGEN UND IHRE ZIELE

Title (fr)

COMPOSITIONS ET PROCEDES RELATIFS A DE NOUVEAUX COMPOSES DE BENZODIAZEPINE ET LEURS CIBLES

Publication

EP 1423122 A4 20081210 (EN)

Application

EP 02794914 A 20020815

Priority

  • US 0226171 W 20020815
  • US 31256001 P 20010815
  • US 31368901 P 20010820
  • US 39667002 P 20020718
  • US 21787802 A 20020813

Abstract (en)

[origin: WO03015703A2] The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regualtion of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like.

IPC 1-7

A61K 31/55; C07D 487/04; G01N 33/48

IPC 8 full level

A61K 31/5513 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); A61P 37/06 (2006.01); C07D 243/14 (2006.01); C07D 243/24 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C12Q 1/02 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP)

A61K 31/5513 (2013.01); A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 37/06 (2017.12); C07D 243/14 (2013.01); C07D 243/24 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01)

Citation (search report)

  • [DA] WO 0066106 A2 20001109 - UNIV MICHIGAN [US], et al
  • [A] WO 9966958 A2 19991229 - CENTRE NAT RECH SCIENT [FR]
  • [A] WO 0151922 A2 20010719 - MITOKOR [US], et al
  • [A] WO 9958117 A1 19991118 - SANOFI SYNTHELABO [FR], et al
  • [A] US 5776946 A 19980707 - MCGEER PATRICK L [CA], et al
  • [A] US 4898861 A 19900206 - MORGAN JAMES I [US], et al
  • [A] TANIMOTO Y ET AL: "BENZODIAZEPINE RECEPTOR AGONISTS MODULATE THYMOCYTE APOPTOSIS THROUGH REDUCTION OF THE MITOCHONDRIAL TRANSMEMBRANE POTENTIAL", JAPANESE JOURNAL OF PHARMACOLOGY, JP, vol. 79, no. 2, 1 January 1999 (1999-01-01), pages 177 - 183, XP000957554, ISSN: 0021-5198
  • [A] BLUM P ET AL: "STIFF-PERSON SYNDROME: AN AUTOIMMUNE DISEASE", MOVEMENT DISORDERS, RAVEN PRESS, NEW YORK, NY, US, vol. 6, no. 1, 1 January 1991 (1991-01-01), pages 12 - 20, XP000957552, ISSN: 0885-3185
  • [A] SCHLUMPF M ET AL: "DELAYED DEVELOPMENTAL IMMUNOTOXICITY OF PRENATAL BENZODIAZEPINES", TOXICOLOGY IN VITRO, ELSEVIER SCIENCE, GB, vol. 8, no. 5, 1 January 1994 (1994-01-01), pages 1061 - 1065, XP000957564, ISSN: 0887-2333
  • [A] SHAWN Y. STEVENS ET AL.: "Non nucleic acis inhibitors of protein-DNA interactions identified through combinatorial chemistry", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 118, 1996, pages 10650 - 10651, XP002499663
  • See references of WO 03015703A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

DOCDB simple family (publication)

WO 03015703 A2 20030227; WO 03015703 A3 20031113; AU 2002332560 B2 20060119; CA 2457405 A1 20030227; EP 1423122 A2 20040602; EP 1423122 A4 20081210; JP 2005502652 A 20050127; MX PA04001421 A 20040603; NO 20041058 L 20040514; NZ 531117 A 20060331

DOCDB simple family (application)

US 0226171 W 20020815; AU 2002332560 A 20020815; CA 2457405 A 20020815; EP 02794914 A 20020815; JP 2003520664 A 20020815; MX PA04001421 A 20020815; NO 20041058 A 20040312; NZ 53111702 A 20020815