EP 1424330 B1 20110928 - ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA
Title (en)
ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA
Title (de)
AKTIVATOR FÜR DEN PEROXISOME PROLIFERATOR-RESPONSIVEN REZEPTOR DELTA
Title (fr)
ACTIVATEUR DU RECEPTEUR DELTA SENSIBLE AU PROLIFERATEUR DE PEROXYSOME
Publication
Application
Priority
- JP 0207897 W 20020802
- JP 2001243734 A 20010810
Abstract (en)
[origin: EP1424330A1] A compound represented by the following general formula (I): <CHEM> (wherein R<1> represents phenyl, etc. which can have substituents selected from the group consisting of C1-8 alkyl, C1-8 alkyl having halogen, halogen, hydroxyl, etc.; R<2> represents C1-8 alkyl, etc.; A represents oxygen, sulfur, etc.; X represents C1-8 alkylene chain, etc.; Y represents C(=O), CH=CH, etc.; R<3>, R<4>, and R<5> each represents hydrogen, C1-8 alkyl, etc.; B represents CH or nitrogen; Z represents oxygen or sulfur; R<6> and R<7> each represents hydrogen, C1-8 alkyl, etc.; and R<8> represents hydrogen or C1-8 alkyl; provided that at least one of R<3>, R<4>, and R<5> is not hydrogen) or a salt of the compound; and a PPAR- delta activator which contains the compound or salt as the active ingredient.
IPC 8 full level
C07D 263/32 (2006.01); A61K 31/421 (2006.01); A61K 31/426 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 5/14 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 19/10 (2006.01); A61P 21/04 (2006.01); A61P 25/28 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/54 (2006.01); C07D 263/62 (2006.01); C07D 277/24 (2006.01); C07D 277/26 (2006.01)
CPC (source: EP KR US)
A61P 3/00 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 5/14 (2017.12 - EP); A61P 5/38 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 19/10 (2017.12 - EP); A61P 21/04 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 27/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 263/32 (2013.01 - EP US); C07D 263/62 (2013.01 - EP US); C07D 277/24 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
EP 1424330 A1 20040602; EP 1424330 A4 20041027; EP 1424330 B1 20110928; AT E526319 T1 20111015; AU 2002323776 B2 20080731; BR 0211844 A 20040831; BR PI0211844 B1 20190827; BR PI0211844 B8 20210525; CA 2457054 A1 20030227; CA 2457054 C 20111011; CN 1330641 C 20070808; CN 1568316 A 20050119; CY 1112130 T1 20151104; DK 1424330 T3 20120116; ES 2372813 T3 20120126; IL 160304 A0 20040725; IL 160304 A 20101230; JP 2009102442 A 20090514; JP 2009280622 A 20091203; JP 4421895 B2 20100224; JP 5097180 B2 20121212; JP WO2003016291 A1 20041202; KR 100901683 B1 20090608; KR 20040023741 A 20040318; MX PA04001258 A 20050606; PT 1424330 E 20111222; US 2005054674 A1 20050310; US 2008009525 A1 20080110; US 2008009631 A1 20080110; US 7265137 B2 20070904; US 7648999 B2 20100119; US 7652045 B2 20100126; WO 03016291 A1 20030227
DOCDB simple family (application)
EP 02755779 A 20020802; AT 02755779 T 20020802; AU 2002323776 A 20020802; BR 0211844 A 20020802; CA 2457054 A 20020802; CN 02820189 A 20020802; CY 111101199 T 20111202; DK 02755779 T 20020802; ES 02755779 T 20020802; IL 16030402 A 20020802; IL 16030404 A 20040210; JP 0207897 W 20020802; JP 2003521216 A 20020802; JP 2009032919 A 20090216; JP 2009203393 A 20090903; KR 20047002008 A 20020802; MX PA04001258 A 20020802; PT 02755779 T 20020802; US 48678304 A 20040323; US 88849207 A 20070731; US 88849307 A 20070731