EP 1427289 B1 20170510 - PULSATILE RELEASE COMPOSITIONS AND METHODS FOR ENHANCED GASTROINTESTINAL DRUG ABSORPTION
Title (en)
PULSATILE RELEASE COMPOSITIONS AND METHODS FOR ENHANCED GASTROINTESTINAL DRUG ABSORPTION
Title (de)
ZUSAMMENSETZUNGEN MIT PULSARTIGER FREIGABE UND VERFAHREN ZUR VERBESSERTEN ARZNEISTOFFABSORPTION IM MAGEN-DARM-TRAKT
Title (fr)
COMPOSITIONS A LIBERATION PULSEE ET PROCEDES POUR AMELIORER L'ABSORPTION GASTRO-INTESTINALE DE MEDICAMENTS
Publication
Application
Priority
- US 0226924 W 20020822
- US 94449301 A 20010822
Abstract (en)
[origin: WO03017940A2] Modified release pharmaceutical formulations and methods for enhanced mucosal drug absorption. The formulation comprises initial population(s) of particles comprising both drug and penetration enhancer which are released at a first location in the gastrointestinal tract, and a subsequent population or populations of particles comprising a penetration enhancer(s) having a delayed release due to a polymeric coating or matrix. This penetration enhancer is released at an additional location( s ) in the intestine downstream from the first location and enhances absorption of the drug when it reaches the additional location(s).
IPC 8 full level
A61K 9/26 (2006.01); A61K 47/12 (2006.01); A61K 9/20 (2006.01); A61K 9/22 (2006.01); A61K 9/24 (2006.01); A61K 9/28 (2006.01); A61K 9/42 (2006.01); A61K 9/48 (2006.01); A61K 9/52 (2006.01); A61K 9/54 (2006.01); A61K 9/66 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 47/04 (2006.01); A61K 47/08 (2006.01); A61K 47/14 (2006.01); A61K 47/16 (2006.01); A61K 47/18 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61K 47/28 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/42 (2006.01); A61K 48/00 (2006.01); A61P 1/04 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61K 9/4808 (2013.01 - EP US); A61P 1/04 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); A61K 9/4891 (2013.01 - EP US)
Citation (examination)
- WO 0066089 A1 20001109 - CIMA LABS INC [US]
- WO 02060415 A1 20020808 - ROEHM GMBH [DE], et al
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03017940 A2 20030306; WO 03017940 A3 20031211; AU 2002332647 B2 20080515; CA 2458442 A1 20030306; CA 2458442 C 20120522; EP 1427289 A2 20040616; EP 1427289 A4 20060628; EP 1427289 B1 20170510; IL 160117 A0 20040620; IL 160117 A 20130324; JP 2005505533 A 20050224; JP 4460290 B2 20100512; US 2003124196 A1 20030703; US 2005196443 A1 20050908; US 2011256217 A1 20111020; US 7576067 B2 20090818
DOCDB simple family (application)
US 0226924 W 20020822; AU 2002332647 A 20020822; CA 2458442 A 20020822; EP 02796423 A 20020822; IL 16011702 A 20020822; IL 16011704 A 20040129; JP 2003522463 A 20020822; US 48567509 A 20090616; US 81404 A 20041201; US 94449301 A 20010822