EP 1427839 A1 20040616 - METHOD FOR THE PRODUCTION OF PHOSPHOLIPIDS
Title (en)
METHOD FOR THE PRODUCTION OF PHOSPHOLIPIDS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PHOSPHOLIPIDEN
Title (fr)
PROCEDE POUR PRODUIRE DES PHOSPHOLIPIDES
Publication
Application
Priority
- DE 10142014 A 20010828
- EP 0209611 W 20020828
Abstract (en)
[origin: WO03020941A1] The invention relates to a method for the production of phospholipids of general formula (I) with the exclusive aid of phospholipase D from a phospholipid mixture and without using organic solvents, wherein phosphatidyl acid is produced in an aqueous, unbuffered phase with phospholipase D and at least one bivalent metal ion in a first step and at least one phospholipid of general formula (I) is produced from the phosphatidyl acid having at least one compound of general formula (II) R<3> - OH in a second step. Phosphatidylserine, phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositeand/or phosphatidylglycerine are obtained as products. In another embodiment of the invention, the PLD is identical or different in both steps of said method, wherein in the latter case the pH values for the first and second steps of the method are different, said values lying particularly between 6.5 and 8.0, especially between 5.0 and 7.5. The novel method makes it possible to easily obtain products with high yields and excellent purity thereby rendering said products suitable for applications in the food industry and pharmaceutical applications.
IPC 1-7
IPC 8 full level
C12P 7/00 (2006.01); C07F 9/10 (2006.01); C12P 7/6481 (2022.01); C12P 9/00 (2006.01); C12P 13/00 (2006.01)
CPC (source: EP US)
C07F 9/10 (2013.01 - EP US); C12P 7/6481 (2013.01 - EP US); C12P 9/00 (2013.01 - EP US); C12P 13/001 (2013.01 - EP US); C12P 13/06 (2013.01 - EP US); C12P 19/44 (2013.01 - EP US)
Citation (search report)
See references of WO 03020941A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03020941 A1 20030313; DE 10142014 A1 20030424; DE 10142014 B4 20041111; EP 1427839 A1 20040616; JP 2005501559 A 20050120; US 2004235119 A1 20041125; US 7067292 B2 20060627
DOCDB simple family (application)
EP 0209611 W 20020828; DE 10142014 A 20010828; EP 02772222 A 20020828; JP 2003525642 A 20020828; US 48814304 A 20040226