EP 1430037 A4 20041117 - ZONISAMIDE INTERMEDIATE AND SYNTHESIS
Title (en)
ZONISAMIDE INTERMEDIATE AND SYNTHESIS
Title (de)
ZONISAMID-ZWISCHENPRODUKT UND -SYNTHESE
Title (fr)
PRODUITS INTERMEDIAIRES DE ZOSINAMIDE ET SYNTHESE Y RELATIVE
Publication
Application
Priority
- US 0227593 W 20020829
- US 31610901 P 20010830
- US 34443901 P 20011024
Abstract (en)
[origin: WO03020708A1] The present invention relates to a novel sulfonation of an intermediate of zonisamide. The sulfonation processes using chlorosulfonic acid as well as acetic anhydride and sulfuric acid in an organic solvent are disclosed. Crystalline forms of benzisoxazole methane sulfonic acid (BOS-H) and its salts (BOS-Na, BOS-Ca, and BOS-Ba) and their novel preparation processes are disclosed.
IPC 1-7
IPC 8 full level
C07D 261/20 (2006.01)
CPC (source: EP)
C07D 261/20 (2013.01)
Citation (search report)
- [E] WO 02070495 A1 20020912 - TEVA PHARMA [IL], et al
- [X] H. UNO: "studies on 3-substituted 1,2-benzisoxazole derivatives. V.", CHEMICAL AND PHARMACEUTICAL BULLETIN., vol. 26, no. 11, 1978, JPPHARMACEUTICAL SOCIETY OF JAPAN. TOKYO., pages 3498 - 503, XP002295955
- See references of WO 03020708A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03020708 A1 20030313; CA 2458905 A1 20030313; EP 1430037 A1 20040623; EP 1430037 A4 20041117; IL 158239 A0 20040512; JP 2005506980 A 20050310
DOCDB simple family (application)
US 0227593 W 20020829; CA 2458905 A 20020829; EP 02768748 A 20020829; IL 15823902 A 20020829; JP 2003524979 A 20020829