EP 1434581 A1 20040707 - 3- HYDROXY-(-4-TRIFLUOROMETHYLPHENYL)-METHYL-7-SPIROCYCLOBUTYL-5,6,7,8-TETRAHYDROQUINOLIN-5-OL DERIVATIVES AND THE USE OF THE SAME AS CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) INHIBITORS
Title (en)
3- HYDROXY-(-4-TRIFLUOROMETHYLPHENYL)-METHYL-7-SPIROCYCLOBUTYL-5,6,7,8-TETRAHYDROQUINOLIN-5-OL DERIVATIVES AND THE USE OF THE SAME AS CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) INHIBITORS
Title (de)
3-¬HYDROXY-(4-TRIFLUOROMETHYLPHENYL)-METHYL -7-SPIROCYCLOBUTYL-5,6,7,8-TETRAHYDROCHINOLIN-5-OL- DERIVATE UND IHRE VERWENDUNG ALS CHOLESTERIN-ESTER-TRANSFER-PROTEIN (CETP) - INHIBITOREN
Title (fr)
DERIVES DE 3- HYDROXY-(-4-TRIFLUOROMETHYLPHENYL)-METHYL-7-SPIROCYCLOBUTYL-5,6,7,8- TETRAHYDROQUINOLIN-5-OL ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE LA PROTEINE DE TRANSFERT DU CHOLESTEROL ESTERIFIE (CETP)
Publication
Application
Priority
- DE 10148436 A 20011001
- EP 0210444 W 20020918
Abstract (en)
[origin: WO03028727A1] The invention relates to substituted tetrahydroquinoline derivatives of formula (I), wherein A represents a radical (a), (b), (c), (d), (e), (f), (g), (h) or -(CH2)2CH3 and B represents a radical (f) or (h), and to the salts of the same. The invention also relates to a method for producing said substances and to the use thereof in pharmaceuticals.
IPC 1-7
IPC 8 full level
C07D 215/20 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 221/20 (2006.01); C07D 409/04 (2006.01)
CPC (source: EP US)
A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 221/20 (2013.01 - EP US); C07D 409/04 (2013.01 - EP US)
Citation (search report)
See references of WO 03028727A1
Designated contracting state (EPC)
DE ES FR GB IT
DOCDB simple family (publication)
WO 03028727 A1 20030410; WO 03028727 A9 20031113; AR 036583 A1 20040915; CA 2462030 A1 20030410; DE 10148436 A1 20030417; DO P2002000457 A 20030415; EP 1434581 A1 20040707; GT 200200195 A 20030822; HN 2002000278 A 20021220; JP 2005508341 A 20050331; PE 20030604 A1 20030907; US 2005043341 A1 20050224; UY 27458 A1 20030430
DOCDB simple family (application)
EP 0210444 W 20020918; AR P020103608 A 20020925; CA 2462030 A 20020918; DE 10148436 A 20011001; DO 2002000457 A 20020902; EP 02772317 A 20020918; GT 200200195 A 20020927; HN 2002000278 A 20021001; JP 2003532059 A 20020918; PE 2002000962 A 20020930; US 49146504 A 20041007; UY 27458 A 20020927