EP 1435953 A4 20050504 - ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF
Title (en)
ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF
Title (de)
ANTI-VESICANS-VERBINDUNGEN UND VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG
Title (fr)
COMPOSES ANTIVESICANTS ET PROCEDES DE FABRICATION ET D'UTILISATION ASSOCIES
Publication
Application
Priority
US 0123562 W 20010726
Abstract (en)
[origin: WO03011292A1] As disclosed herein, the present invention provides a compound having the structural formula (I) wherein R<1>, R<2>, R<3>, and R<4> are each independently H, or a methyl, halo, trifluoromethyl, nitro, alkyloxy, or acyloxy group, or a pharmaceutically acceptable salt or prodrug thereof. Also disclosed are compounds, compositions, methods and kits for treating, preventing, or inhibiting injuries induced by a vesicant agent, such as bis-2-chloroethylsulfide (HD). Additionally, protectants and decontaminants are disclosed.
IPC 1-7
A61K 31/44; A61K 31/4425; A61K 31/47; C07D 213/89; C07D 215/60; A61P 39/00
IPC 8 full level
C07D 213/89 (2006.01); C07D 215/60 (2006.01)
CPC (source: EP)
A61P 39/00 (2017.12); C07D 213/89 (2013.01); C07D 215/60 (2013.01)
Citation (search report)
- [X] US 3961054 A 19760601 - FURIA THOMAS E, et al
- [X] US 3890309 A 19750617 - OCHIAI MICHIHIKO, et al
- [X] US 3850939 A 19741126 - ELSLAGER E, et al
- [X] LIN, AI J.: "2-Mercaptopyridine-N-oxides and 2-mercaptoquinoline-N-oxides as potential catalytic deactivators of mustards", MEDICAL DEFENSE BIOSCIENCE REVIEW, PROCEEDINGS, BALTIMORE, MAY 12-16, 1996 , VOLUME 2, 893-898 PUBLISHER: NATIONAL TECHNICAL INFORMATION SERVICE, SPRINGFIELD, VA. CODEN: 64UTAN, 1996, XP008044087
- [X] DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NAKANISHI, MICHIO ET AL: "2,2'-Dithiobis(pyridine)-1,1'-dioxide", XP002320594, retrieved from STN Database accession no. 1973:431906 & JP 48006467B B4
- [X] DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NAKANISHI, MICHIO ET AL: "Composition repugnant to rodents", XP002320595, retrieved from STN Database accession no. 1975:402371 & JP 49034809B B4
- See references of WO 03011292A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 03011292 A1 20030213; CA 2459774 A1 20030213; EP 1435953 A1 20040714; EP 1435953 A4 20050504
DOCDB simple family (application)
US 0123562 W 20010726; CA 2459774 A 20010726; EP 01967947 A 20010726