EP 1436329 A1 20040714 - ANTI-PDGF ANTIBODIES AND METHODS FOR PRODUCING ENGINEERED ANTIBODIES
Title (en)
ANTI-PDGF ANTIBODIES AND METHODS FOR PRODUCING ENGINEERED ANTIBODIES
Title (de)
ANTI-PDGF-ANTIKÖRPER UND VERFAHREN ZUR HERSTELLUNG KONSTRUIERTER ANTIKÖRPER
Title (fr)
ANTICORPS ANTI-PDGF ET PROCEDES DE PRODUCTION D'ANTICORPS MIS AU POINT
Publication
Application
Priority
- US 0230086 W 20020920
- US 32353701 P 20010920
- US 32354401 P 20010920
- US 37999402 P 20020513
Abstract (en)
[origin: WO03025019A1] Methods of making and selecting engineered antibodies and/or antibody fragments provide maximized binding affinity for a predetermined target and minimized immunogenicity when such antibodies are administered to a target species. Libraries containing variants of the engineered antibodies are also provided. In particularly useful embodiments, anti-PGDF antibodies and compositions are produced which are useful in the treatment of various cancers.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 16/22 (2006.01); C07K 16/26 (2006.01); C07K 16/46 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07K 16/22 (2013.01); C07K 16/464 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03025019 A1 20030327; WO 03025019 A8 20040401; WO 03025019 A9 20040506; CA 2460587 A1 20030327; EP 1436329 A1 20040714; EP 1436329 A4 20050427; JP 2005512962 A 20050512
DOCDB simple family (application)
US 0230086 W 20020920; CA 2460587 A 20020920; EP 02775937 A 20020920; JP 2003528864 A 20020920