EP 1443902 A2 20040811 - METHOD FOR PRODUCING STABLE SOLUTIONS OF PHENOLIC SUBSTANCES AND RESULTING SOLUTIONS
Title (en)
METHOD FOR PRODUCING STABLE SOLUTIONS OF PHENOLIC SUBSTANCES AND RESULTING SOLUTIONS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON STABILEN LÖSUNGEN PHENOLISCHER SUBSTANZEN UND RESULTIERENDE LÖSUNGEN
Title (fr)
PROCEDE DE PRODUCTION DE SOLUTIONS STABLES DE SUBSTANCES PHENOLIQUES ET LES SOLUTIONS EN RESULTANT
Publication
Application
Priority
- FR 0203922 W 20021115
- FR 0114796 A 20011115
Abstract (en)
[origin: WO03041687A2] The invention concerns the field of therapeutic chemistry and more particularly the field of pharmaceutical technology. More specifically, the invention concerns a novel method for producing stabilized antioxidant-free solutions based on phenolic substances which consists in: deoxygenation of the solutions with an inert gas, and in deoxygenation of gas holdups of the vessels, of the manufacturing pipes and inerting of ampoules and flasks containing the solute with a dense inert rare gas such as argon, at low temperature and with pH adjusted above 3.0 and below 5.0 to obtain stable solutions of phenolic substances containing not more than 0.02 ppm of oxygen in the solution, which is filtered by double sterilizing filtration. The invention is useful for human or animal therapeutic treatment.
IPC 1-7
IPC 8 full level
A61K 9/08 (2006.01); A61K 31/137 (2006.01)
CPC (source: EP US)
A61K 9/08 (2013.01 - EP US); A61K 31/137 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03041687 A2 20030522; WO 03041687 A3 20040304; EP 1443902 A2 20040811; FR 2832063 A1 20030516; FR 2832063 B1 20040827; US 2005070613 A1 20050331; US 7199269 B2 20070403
DOCDB simple family (application)
FR 0203922 W 20021115; EP 02803055 A 20021115; FR 0114796 A 20011115; US 49584104 A 20040715