EP 1446008 A4 20060816 - COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE
Title (en)
COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR GESTEUERTEN FREISETZUNG
Title (fr)
COMPOSITIONS ET PROCEDE POUR LIBERATION CONTROLEE
Publication
Application
Priority
- US 0233558 W 20021017
- US 33634401 P 20011018
Abstract (en)
[origin: WO03060142A2] Methods and compositions are provided for the controlled release of an active agent. The composition includes an oligonucleotide scaffold and a substantially complementary oligonucleotide factor. An active agent is attached to the oligonucleotide factor. The two oligonucleotides are differentially degradable, so that degradation of the scaffold occurs a faster rate than the degradation of the factor. As the scaffold degrades, the factor is released. The active agent can be a therapeutic agent, or a diagnostic agent.
IPC 1-7
C12Q 1/34; A01N 37/18; A01N 43/04; C07H 21/00; C07H 21/02; C07H 21/04; C12Q 1/68; G01N 33/58
IPC 8 full level
A61K 47/48 (2006.01); A01N 37/18 (2006.01); A01N 43/04 (2006.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 31/711 (2006.01); A61K 45/00 (2006.01); A61K 47/26 (2006.01); A61K 47/36 (2006.01); A61K 48/00 (2006.01); A61P 25/04 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); A61P 31/14 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12Q 1/34 (2006.01); C12Q 1/44 (2006.01); C12Q 1/68 (2006.01); G01N 33/58 (2006.01)
IPC 8 main group level
C12Q (2006.01)
CPC (source: EP)
A61P 25/04 (2017.12); A61P 31/04 (2017.12); A61P 31/10 (2017.12); A61P 31/14 (2017.12); A61P 35/00 (2017.12); A61P 37/06 (2017.12); C12N 15/111 (2013.01); C12Q 1/34 (2013.01); G01N 33/58 (2013.01); C12N 2310/11 (2013.01); C12N 2310/13 (2013.01); C12N 2310/317 (2013.01); C12N 2320/32 (2013.01)
Citation (search report)
- [DY] WO 9852614 A2 19981126 - UNIV LELAND STANFORD JUNIOR [US], et al
- [DYX] WO 0124775 A1 20010412 - ESSENTIA BIOSYSTEMS INC [US], et al
- [PX] US 6395029 B1 20020528 - LEVY ROBERT J [US]
- [PX] US 6333194 B1 20011225 - LEVY ROBERT J [US], et al
- [E] WO 03024455 A2 20030327 - CONTROL DELIVERY SYS INC [US], et al
- [E] WO 03030943 A1 20030417 - UNIV BRITISH COLUMBIA [CA], et al
- [A] US 6232068 B1 20010515 - LINSLEY PETER S [US], et al
- [A] US 5985554 A 19991116 - TANIMURA HIROSHI [JP], et al
- [Y] CASSIDY R A ET AL: "Triplex formation by psoralen-conjugated chimeric oligonucleoside methylphosphonates", BIOCHEMISTRY 25 JUL 2000 UNITED STATES, vol. 39, no. 29, 25 July 2000 (2000-07-25), pages 8683 - 8691, XP002355044, ISSN: 0006-2960
- [A] SOHAIL M ET AL: "Antisense arrays", MOLECULAR CELL BIOLOGY RESEARCH COMMUNICATIONS, vol. 3, no. 2, February 2000 (2000-02-01), pages 67 - 72, XP002377138, ISSN: 1522-4724
- [X] MIYASHIRO H ET AL: "Analysis of the RNase H activity by fluorescence resonance energy transfer.", NUCLEIC ACIDS SYMPOSIUM SERIES. 2000, no. 44, 2000, pages 55 - 56, XP002377139, ISSN: 0261-3166
- [X] BIGGINS J B ET AL: "A continuous assay for DNA cleavage: the application of break lights to enediynes, iron-dependent agents, and nucleases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 97, no. 25, 5 December 2000 (2000-12-05), pages 13537 - 13542, XP001094000, ISSN: 0027-8424
- See references of WO 03060142A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03060142 A2 20030724; WO 03060142 A3 20040212; WO 03060142 A9 20030821; AU 2002365136 A1 20030730; AU 2002365136 A8 20030730; CA 2464131 A1 20030724; EP 1446008 A2 20040818; EP 1446008 A4 20060816; JP 2005523890 A 20050811
DOCDB simple family (application)
US 0233558 W 20021017; AU 2002365136 A 20021017; CA 2464131 A 20021017; EP 02803289 A 20021017; JP 2003560224 A 20021017