EP 1446014 A4 20041208 - INTRODUCTION OF THE WLDs GENE FOR PREVENTION OF AXONAL DEGENERATION IN NEUROLOGICAL DISEASES
Title (en)
INTRODUCTION OF THE WLDs GENE FOR PREVENTION OF AXONAL DEGENERATION IN NEUROLOGICAL DISEASES
Title (de)
EINFÜHRUNG DES WLDS-GENS ZUR VORBEUGUNG DER AXONDEGENERATION BEI NEUROLOGISCHEN ERKRANKUNGEN
Title (fr)
INTRODUCTION DU GENE WLDS POUR LA PREVENTION DE LA DEGENERESCENCE AXONALE DANS LES MALADIES NEUROLOGIQUES
Publication
Application
Priority
- US 0231078 W 20021001
- US 32635401 P 20011001
Abstract (en)
[origin: WO03029414A2] Polypeptides that can protect axons from axon degeneration and methods of use of the polypeptides are presented. Polynucleotides that can protect axons from axon degeneration and methods of use of the polynucleotides are presented. In addition, polynucleotides that encode the polypeptides referred to above are presented. Further, pharmaceutical compositions to treat conditions are presented.
IPC 1-7
A01N 63/00; A01N 65/00; A01N 43/04; A61K 48/00; A61K 31/70; C12N 15/00; C12N 15/09; C12N 15/63; C12N 15/70; C12N 15/74; C12N 15/85; C12N 15/12; C07K 14/47; C07K 19/00; C12N 15/62; C12Q 1/68; A61K 38/17; A61K 31/713; A61P 25/00
IPC 8 full level
C07K 14/47 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); A61P 25/28 (2017.12); C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 2799/022 (2013.01)
Citation (search report)
- [X] WO 0164907 A2 20010907 - INCYTE GENOMICS INC [US], et al
- [X] CONFORTI L ET AL: "A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 97, no. 21, 10 October 2000 (2000-10-10), pages 11377 - 11382, XP002953257, ISSN: 0027-8424
- [X] WANG M-S ET AL: "The gene for low Wallerian degeneration (WldS) is also protective against vincristine neuropathy", NEUROBIOLOGY OF DISEASE, BLACKWELL SCIENTIFIC PUBLICATIONS, OXFORD, GB, vol. 8, 20 December 2000 (2000-12-20), pages 155 - 161, XP002953259, ISSN: 0969-9961
- [X] FERNANDO S ET AL: "Characterization of the human homologue of a candidate gene for slow Wallerian degeneration", AMERICAN JOURNAL OF HUMAN GENETICS, AMERICAN SOCIETY OF HUMAN GENETICS, CHICAGO, IL, US, vol. 67, no. SUPPLEMENT 2, October 2000 (2000-10-01), pages 178, XP002953261, ISSN: 0002-9297
- [A] WANG M-S ET AL: "Pathogenesis of axonal degeneration: parallels between Wallerian degeneration and vincristine neuropathy", JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, NEW YORK, NY, US, vol. 59, no. 7, July 2000 (2000-07-01), pages 599 - 606, XP002953258, ISSN: 0022-3069
- [PX] DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2001, COLEMAN M P ET AL: "Protecting axons: The molecular basis of slow Wallerian degeneration", XP002299951, Database accession no. PREV200200038753 & DATABASE GENBANK 2 October 2000 (2000-10-02), CONFORTI; ET AL: "Mus musculus UFD2/D4COLE1E fusion protein mRNA", XP002953260, retrieved from GENBANK Database accession no. AF260924 & SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 27, no. 2, 2001, 31ST ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; SAN DIEGO, CALIFORNIA, USA; NOVEMBER 10-15, 2001, pages 2623, ISSN: 0190-5295
- See references of WO 03029414A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03029414 A2 20030410; WO 03029414 A3 20031218; CA 2462632 A1 20030410; EP 1446014 A2 20040818; EP 1446014 A4 20041208
DOCDB simple family (application)
US 0231078 W 20021001; CA 2462632 A 20021001; EP 02800391 A 20021001