EP 1446161 A2 20040818 - MEDICINAL COMBINATION OF BIGUANINE (METFORMIN) AND ARGININE
Title (en)
MEDICINAL COMBINATION OF BIGUANINE (METFORMIN) AND ARGININE
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG EINES BIGUANIN (METFORMIN) UND ARGININ
Title (fr)
ASSOCIATION MEDICAMENTEUSE D'UNE BIGUANINE (METFORMINE) ET D'ARGININE
Publication
Application
Priority
- FR 0104236 W 20011231
- FR 0017331 A 20001229
Abstract (en)
[origin: WO02053091A2] The invention concerns the use as medicine of an active compound of general formula A'<u>-----</u> V'<u>---- </u>C', capable of restoring at least the entity A by cleaving the corresponding bonds between A' and V', and optionally capable of restoring likewise the entities V and C by cleaving in vivo the bond V'----- C' or V'- C' provided that: V is a vectorizing biogenic compound, of general formula X-R-Y, wherein R represents a hydrocarbon chain of 2 to 10 carbon atoms, aliphatic, cyclic, or alicyclic, saturated or unsaturated, optionally substituted by C1-C5 alkyl groups, and/or hydroxyl groups; X and Y are each a free acid, amine, or alcohol function. A and C are two respectively different active principles, one of which comprises a chemical function complementary to the function X, capable of reacting with the latter to produce a bond, ionic A'---- V' or covalent A - V, cleavable in vivo, and the other comprises a chemical function complementary to the function Y, capable of reacting with the latter to produce a bond, ionic V'---- C or covalent V'- C', cleavable in vivo
IPC 1-7
IPC 8 full level
A61K 31/198 (2006.01); A61K 47/48 (2006.01); A61P 3/10 (2006.01); A61P 5/00 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61K 47/54 (2017.07 - EP US); A61P 3/10 (2017.12 - EP); A61P 5/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 02053091A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02053091 A2 20020711; WO 02053091 A3 20040610; CA 2435483 A1 20020711; EP 1446161 A2 20040818; FR 2818908 A1 20020705; FR 2818908 B1 20040402; JP 2004517106 A 20040610; NZ 527207 A 20060428; RU 2003123490 A 20050120; US 2004058854 A1 20040325; US 2008021015 A1 20080124; ZA 200207757 B 20040726
DOCDB simple family (application)
FR 0104236 W 20011231; CA 2435483 A 20011231; EP 01990622 A 20011231; FR 0017331 A 20001229; JP 2002554042 A 20011231; NZ 52720701 A 20011231; RU 2003123490 A 20011231; US 46599403 A 20031003; US 87950507 A 20070718; ZA 200207757 A 20020926