EP 1448579 A1 20040825 - PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS
Title (en)
PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS
Title (de)
PHOSPHOLIPID-DERIVATE VON NUCLEOSIDEN ALS ANTITUMORALE ARZNEIMITTEL
Title (fr)
DERIVES PHOSPHOLIPIDES DE NUCLEOSIDES UTILISES COMME MEDICAMENTS ANTITUMORAUX
Publication
Application
Priority
- DE 10156910 A 20011121
- DE 10209564 A 20020304
- EP 0212908 W 20021118
Abstract (en)
[origin: WO03044035A1] The invention relates to medicaments containing phospholipid derivatives preferably of unnatural nucleosides of general formula (I), wherein R1 represents an alkyl chain with 10-14 carbon atoms, R2 represents an alkyl chain with 8-12 carbon atoms, n represents a whole number from 0 to 2, R3 represents a hydroxy group, R4 and R5 represent hydrogen and B is a 5-fluorouracil. Said derivatives are used as antitumoral or antiproliferative active ingredients for the prophylaxis and/or curative, palliative or supportive treatment of tumor diseases or neoplasia such as carcinoma, sarcoma, lymphoma or leukemia, and also as monotherapeutic or monoprophylactic agents in free or fixed combination with other prophylactic or therapeutic modalities.
IPC 1-7
IPC 8 full level
C07H 19/10 (2006.01)
CPC (source: EP US)
C07H 19/10 (2013.01 - EP US)
Citation (search report)
See references of WO 03044035A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03044035 A1 20030530; AU 2002356672 A1 20030610; CA 2468099 A1 20030530; CN 1615314 A 20050511; EP 1448579 A1 20040825; MX PA04004712 A 20050620; NZ 533094 A 20060127; US 2005090659 A1 20050428
DOCDB simple family (application)
EP 0212908 W 20021118; AU 2002356672 A 20021118; CA 2468099 A 20021118; CN 02827219 A 20021118; EP 02803379 A 20021118; MX PA04004712 A 20021118; NZ 53309402 A 20021118; US 49649904 A 20041215