Global Patent Index - EP 1448792 A1

EP 1448792 A1 20040825 - DIAGNOSIS KIT, DNA CHIP, AND METHODS FOR DIAGNOSING OR SUPERVISING THE TREATMENT OF TESTICULAR CANCER

Title (en)

DIAGNOSIS KIT, DNA CHIP, AND METHODS FOR DIAGNOSING OR SUPERVISING THE TREATMENT OF TESTICULAR CANCER

Title (de)

DIAGNOSE-KIT, DNS-CHIP SOWIE VERFAHREN ZUR DIAGNOSTIK ODER BEHANDLUNGSKONTROLLE BEI HODENKREBS

Title (fr)

KIT DE DIAGNOSTIC, PUCE ADN ET METHODES POUR ETABLIR LE DIAGNOSTIC OU EFFECTUER LE CONTROLE DU TRAITEMENT D'UN CANCER DU TESTICULE

Publication

EP 1448792 A1 20040825 (DE)

Application

EP 01274739 A 20011122

Priority

EP 0113606 W 20011122

Abstract (en)

[origin: US2005118591A1] The invention relates to a diagnosis kit, a DNA chip, and to methods for diagnosing or supervising the treatment of testicular cancer, which are of greatest importance, in particular, within the scope of cancer prevention and post-treatment. The invention is essentially characterized in that the mRNA of testicular tumor markers is detected in a blood sample, whereby the tumor markers depict a tumor-associated gene expression. To this end, particularly beta-hCG, AFP, PLAP or GCAP come into question. The detection of the mRNA is carried out by reverse transcription in cDNA and by subsequently amplifying selected segments of the cDNA by means of polymerase chain reaction.

IPC 1-7

C12Q 1/68; B01J 19/00; G01N 33/50

IPC 8 full level

C07K 16/30 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01)

CPC (source: EP US)

C07K 16/30 (2013.01 - EP US); G01N 33/54326 (2013.01 - EP US); G01N 33/56966 (2013.01 - EP US); G01N 33/57492 (2013.01 - EP US)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

US 2005118591 A1 20050602; AU 2002219137 A1 20030610; EP 1448792 A1 20040825; WO 03044224 A1 20030530

DOCDB simple family (application)

US 49641004 A 20041012; AU 2002219137 A 20011122; EP 0113606 W 20011122; EP 01274739 A 20011122