EP 1451590 A2 20040901 - PEPTIDES AND METHOD FOR DETECTING ALZHEIMER'S DISEASE AND DIFFERENTIATING ALZHEIMER'S DISEASE FROM OTHER DEMENTIAL DISEASES
Title (en)
PEPTIDES AND METHOD FOR DETECTING ALZHEIMER'S DISEASE AND DIFFERENTIATING ALZHEIMER'S DISEASE FROM OTHER DEMENTIAL DISEASES
Title (de)
PEPTIDE UND VERFAHREN ZUM NACHWEIS VON MORBUS ALZHEIMER UND ZUR UNTERSCHEIDUNG VON MORBUS ALZHEIMER GEGENÜBER ANDEREN DEMENZIELLEN ERKRANKUNGEN
Title (fr)
PEPTIDES ET PROCEDE PERMETTANT DE DETECTER LA MALADIE D'ALZHEIMER ET DE DIFFERENCIER CETTE MALADIE PAR RAPPORT AUX AUTRES MALADIES DEMENCIELLES
Publication
Application
Priority
- DE 0204360 W 20021127
- DE 10158180 A 20011128
Abstract (en)
[origin: WO03048775A2] The invention relates to defined peptides and the quantitative determination thereof in the body fluids of patients suffering from Alzheimer's disease in relation to the concentration thereof in a control group of patients who are healthy or suffer from other demential diseases. The inventive peptides originate from the C3f fragment of the complement C3 protein precursor with the corresponding gene and are modified in a specific manner and are optionally post-translationally or chemically modified. Modification occurs with respect to the concentrations of said peptides in patients in a manner which is specific to each peptide when compared with the control group. A specific and significant modification of the concentration of said peptides in relation to the concentration thereof in healthy persons indicates a differentiation with respect to Alzheimer's disease. The invention also relates to the use of said peptides as a progress control, and in the development of diagnostic and therapeutic agents.
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 25/28 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 30/88 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP US)
A61P 25/28 (2017.12 - EP); C07K 14/472 (2013.01 - EP US); G01N 33/6896 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); G01N 2800/2821 (2013.01 - EP US)
Citation (search report)
See references of WO 03048775A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03048775 A2 20030612; WO 03048775 A3 20040129; AU 2002363825 A1 20030617; AU 2002363825 A8 20030617; CA 2467073 A1 20030612; DE 10158180 A1 20030911; DE 10295664 D2 20041014; EP 1451590 A2 20040901; JP 2005511063 A 20050428; US 2005048584 A1 20050303
DOCDB simple family (application)
DE 0204360 W 20021127; AU 2002363825 A 20021127; CA 2467073 A 20021127; DE 10158180 A 20011128; DE 10295664 T 20021127; EP 02798252 A 20021127; JP 2003549919 A 20021127; US 49707304 A 20041026