EP 1461005 A2 20040929 - STABLE ORAL COMPOSITIONS COMPRISING CASEIN PHOSPHOPEPTIDE COMPLEXES AND FLUORIDE
Title (en)
STABLE ORAL COMPOSITIONS COMPRISING CASEIN PHOSPHOPEPTIDE COMPLEXES AND FLUORIDE
Title (de)
STABILE, CASEIN-PHOSPHOPEPTIDKOMPLEXE UND FLUORID ENTHALTENDE MUNDPFLEGEZUSAMMENSETZUNGEN
Title (fr)
COMPOSITIONS ADMINISTREES PAR VOIE ORALE STABLES COMPRENANT DES COMPLEXES DE PHOSPHOPEPTIDES DE CASEINE ET DE FLUORURE
Publication
Application
Priority
- US 0239599 W 20021211
- US 34591202 P 20020103
Abstract (en)
[origin: WO03059303A2] The present invention relates to oral care compositions, especially toothpastes, comprising: a safe and effective amount of phosphopeptide-amorphous calcium phosphate complex ("PP-ACP"); a safe and effective amount of a fluoride ion source; a safe and effective amount of a phosphate buffer; a pharmaceutically-acceptable topical, oral carrier; wherein the pH of the final composition is greater than 8 to about 12 and the composition has improved fluoride stability. This invention further relates to a method of maintaining the fluoride levels in an oral care composition comprising a safe and effective amount of PP-ACP, a safe and effective amount of a fluoride ion source, and a pharmaceutically-acceptable topical, oral carrier, by adjusting the pH of the composition to greater than 8 to about 12 and by adding, to the composition, a safe and effective amount of a phosphate buffer.
IPC 1-7
IPC 8 full level
A61K 8/21 (2006.01); A61K 8/24 (2006.01); A61K 8/64 (2006.01); A61Q 11/00 (2006.01)
CPC (source: EP US)
A61K 8/21 (2013.01 - EP US); A61K 8/24 (2013.01 - EP US); A61K 8/64 (2013.01 - EP US); A61Q 11/00 (2013.01 - EP US)
Citation (search report)
See references of WO 03059303A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03059303 A2 20030724; WO 03059303 A3 20031204; AU 2002360556 A1 20030730; CA 2469498 A1 20030724; CA 2469498 C 20090602; CN 1610533 A 20050427; EP 1461005 A2 20040929; MX PA04006541 A 20041004; US 2003152525 A1 20030814
DOCDB simple family (application)
US 0239599 W 20021211; AU 2002360556 A 20021211; CA 2469498 A 20021211; CN 02826425 A 20021211; EP 02795820 A 20021211; MX PA04006541 A 20021211; US 32120902 A 20021217