EP 1469889 A2 20041027 - EX-VIVO GENE THERAPY OF DIABETES USING IAP POLYPEPTIDES
Title (en)
EX-VIVO GENE THERAPY OF DIABETES USING IAP POLYPEPTIDES
Title (de)
EX-VIVO GENTHERAPIE VON DIABETES MIT HILFE VON IAP POLYPEPTIDEN
Title (fr)
THERAPIE GENIQUE EX-VIVO POUR LE TRAITEMENT DU DIABETE UTILISANT DES POLYPEPTIDES IPA
Publication
Application
Priority
- IB 0300597 W 20030123
- US 35078302 P 20020123
Abstract (en)
[origin: WO03061551A2] The invention features methods for the treatment of diabetes by administering a IAP nucleic acid sequence to a subject. One methodincludes the steps of. (a) providing one or more insulin-producing cells or one or more precursor cells capable of producing progeny cells tha tproduce insulin; (b) transducing the cells with a nucleic acid sequence encoding an IAP plypeptide, the nucleic acid sequence postioned for expression of the IAP polypeptide in the cells, wherein expression of the IAP polypeptide increases survival of the cells relative to untreated control cells; and (c)transplanting the cells from step (b) that have been transduced with anucleic acid sequence encoding an IAP polypeptide into the individual, wherein the cells produce insulin in amounts sufficient to treat diabetes in the individual.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); A61P 3/10 (2006.01)
CPC (source: EP)
A61K 48/005 (2013.01); A61K 48/0075 (2013.01); A61P 3/10 (2017.12)
Citation (search report)
See references of WO 03061551A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03061551 A2 20030731; WO 03061551 A3 20031113; AU 2003237031 A1 20030902; CA 2472333 A1 20030731; EP 1469889 A2 20041027
DOCDB simple family (application)
IB 0300597 W 20030123; AU 2003237031 A 20030123; CA 2472333 A 20030123; EP 03731800 A 20030123