Global Patent Index - EP 1470223 A4

EP 1470223 A4 20050406 - HOMOLOGOUS 28-KILODALTON IMMUNODOMINANT PROTEIN GENES OF EHRLICHIA CANIS AND USES THEREOF

Title (en)

HOMOLOGOUS 28-KILODALTON IMMUNODOMINANT PROTEIN GENES OF EHRLICHIA CANIS AND USES THEREOF

Title (de)

HOMOLOGES 28-KILODALTON, IMMUNODOMINANTES, FÜR EIN PROTEIN KODIERENDE GENE AUS EHRLICHIA CANIS UND DEREN ANWENDUNGEN

Title (fr)

GENES PROTEIQUES HOMOLOGUES IMMUNODOMINANTS DE 28-KILODALTONS DE EHRLICHIA CANIS ET LEURS UTILISATIONS

Publication

EP 1470223 A4 20050406 (EN)

Application

EP 99962885 A 19991124

Priority

  • US 9928075 W 19991124
  • US 20145898 A 19981130
  • US 26135899 A 19990303

Abstract (en)

[origin: WO0032745A2] The present invention is directed to the cloning, sequencing and expression of homologous immnunoreactive 28-kDa protein genes, ECa28-1 and ECa28SA3, from a polymorphic multiple gene family of Ehrlichia canis. A complete sequence of another 28-kDa protein gene, ECaSA2, is also provided. Further disclosed is a multigene locus encoding all five homologous 28-kDa protein genes of Ehrlichia canis. Recombinant Ehrlichia canis 28-kDa proteins react with convalescent phase antiserum from an E. canis-infected dog.

IPC 1-7

C12N 15/00; A61K 39/00; A61K 39/395; C07H 21/02; C07K 1/00; C12N 1/20; C12P 21/06

IPC 8 full level

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 48/00 (2006.01); A61P 31/04 (2006.01); A61P 33/00 (2006.01); C07K 14/195 (2006.01); C07K 14/29 (2006.01); C07K 16/12 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/31 (2006.01); C12N 15/63 (2006.01); C12P 21/02 (2006.01)

CPC (source: EP)

A61P 31/04 (2018.01); A61P 33/00 (2018.01); A61P 37/04 (2018.01); C07K 14/29 (2013.01); A61K 2039/52 (2013.01); Y02A 50/30 (2018.01)

Citation (search report)

  • [PX] WO 9913720 A1 19990325 - UNIV OHIO STATE [US]
  • [A] OHASHI ET AL.: "Immunodominant major outer membrane proteins of Ehrlichia chaffensis are encoded by a polymorphic multigene family", INFECTION AND IMMUNITY, vol. 66, no. 1, January 1998 (1998-01-01), pages 132 - 139, XP002316127
  • See also references of WO 0032745A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0032745 A2 20000608; WO 0032745 A3 20040521; AU 1923400 A 20000619; AU 762315 B2 20030619; BR 9916141 A 20011204; CA 2352466 A1 20000608; CN 1535314 A 20041006; EP 1470223 A2 20041027; EP 1470223 A4 20050406; IL 143415 D0 20020421; JP 2003527073 A 20030916; NZ 511922 A 20031031; RU 2237716 C2 20041010; TW I221481 B 20041001

DOCDB simple family (application)

US 9928075 W 19991124; AU 1923400 A 19991124; BR 9916141 A 19991124; CA 2352466 A 19991124; CN 99813782 A 19991124; EP 99962885 A 19991124; IL 14341599 A 19991124; JP 2000585376 A 19991124; NZ 51192299 A 19991124; RU 2001117860 A 19991124; TW 88120620 A 19991125