EP 1472208 A1 20041103 - NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Title (en)

NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Title (de)

NEUE 3-ARYL-2,5-DIHYDROXY-1,4-BENZOCHINONDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN, DIE DIESE ENTHALTEN

Title (fr)

NOUVEAUX DERIVES DE 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT

Publication

EP 1472208 A1 20041103 (FR)

Application

EP 03737340 A 20030204

Priority

FR 0300331 W 20030204
FR 0201409 A 20020206

Abstract (en)

[origin: WO03066561A1] The invention concerns a compound of formula (I), wherein: R1 and R2, identical or different, represent each a hydrogen atom or an acyl or alkyl group; Ar represents an aryl or heteroaryl group; A represents a group selected from formula (II); R4 represents a hydrogen atom or an alkyl group; R5 represents a hydrogen atom or a group selected among alkyl, aryl and heteroaryl; R3 represents an aryl, heteroaryl, dicyclopropylmethyl or benzhydryl group, or A-R3 represents an optionally substituted naphthyl group, excluding 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-phenylethenyl)-1,4-benzoquinone, 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-naphthyl)-1,4-benzoquinone, and 2,5-dihydroxy-3-(2-naphthyl)-6-phenyl-1,4-benzoquinone. The inventive compound is useful for preparing medicines.

IPC 1-7

C07C 50/28; C07D 213/50; A61K 31/122; A61P 3/10

IPC 8 full level

A61K 31/122 (2006.01); A61K 31/222 (2006.01); A61K 31/4402 (2006.01); A61P 3/10 (2006.01); C07C 45/00 (2006.01); C07C 45/28 (2006.01); C07C 46/00 (2006.01); C07C 46/10 (2006.01); C07C 50/28 (2006.01); C07C 50/30 (2006.01); C07D 213/50 (2006.01)

CPC (source: EP KR US)

A61K 31/122 (2013.01 - KR); A61P 3/10 (2017.12 - EP); C07C 45/00 (2013.01 - EP US); C07C 45/28 (2013.01 - EP US); C07C 46/00 (2013.01 - EP US); C07C 50/28 (2013.01 - EP KR US); C07D 213/50 (2013.01 - EP US)

C-Set (source: EP US)

Citation (search report)

See references of WO 03066561A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

DOCDB simple family (publication)

WO 03066561 A1 20030814; AR 038397 A1 20050112; AU 2003226860 A1 20030902; AU 2003226860 B2 20080626; AU 2003226860 B8 20080710; AU 2003226860 B9 20080814; BR 0307465 A 20041109; CA 2474533 A1 20030814; CN 1274655 C 20060913; CN 1628088 A 20050615; EA 006775 B1 20060428; EA 200400992 A1 20050224; EP 1472208 A1 20041103; FR 2835523 A1 20030808; FR 2835523 B1 20040416; GE P20063900 B 20060810; HK 1078566 A1 20060317; JP 2005517001 A 20050609; JP 4098248 B2 20080611; KR 100605805 B1 20060801; KR 20040086352 A 20041008; MA 27103 A1 20041220; MX PA04007684 A 20050713; NO 20043532 L 20040824; NZ 534099 A 20060929; PL 370773 A1 20050530; UA 79448 C2 20070625; US 2005085644 A1 20050421; ZA 200405446 B 20050708

DOCDB simple family (application)

FR 0300331 W 20030204; AR P030100368 A 20030206; AU 2003226860 A 20030204; BR 0307465 A 20030204; CA 2474533 A 20030204; CN 03803177 A 20030204; EA 200400992 A 20030204; EP 03737340 A 20030204; FR 0201409 A 20020206; GE AU2003008395 A 20030204; HK 05110489 A 20051121; JP 2003565937 A 20030204; KR 20047012152 A 20030204; MA 27795 A 20040721; MX PA04007684 A 20030204; NO 20043532 A 20040824; NZ 53409903 A 20030204; PL 37077303 A 20030204; UA 20040907252 A 20030204; US 50352704 A 20040804; ZA 200405446 A 20040708