Global Patent Index - EP 1472287 A4

EP 1472287 A4 20051005 - RHAMNOSE BINDING PROTEIN

Title (en)

RHAMNOSE BINDING PROTEIN

Title (de)

RHAMNOSEBINDUNGS PROTEIN

Title (fr)

PROTEINE FIXANT LE RHAMNOSE

Publication

EP 1472287 A4 20051005 (EN)

Application

EP 03700718 A 20030207

Priority

  • AU 0300135 W 20030207
  • AU PS036402 A 20020207

Abstract (en)

[origin: WO03066679A1] An isolated RBP with at least one of the following characteristics: a a molecular weight of approximately 65-70 kDa and more preferably 66-69kDa b a pI of greater than 10 or less than 3 c a dissociation constant of approximately 1.5 x 10-6 when bound to the rhamnose moiety of solamargine d adapted to bind to a rhamnose affinity column prepared according to example 1 and under the conditions set out therein e adapted to be eluted from the column in example 1 with a 100mM rhamnose solution f insoluble in aqueous solution and g soluble in highly denaturing buffers containing greater that approximately 2% surfactant.

IPC 1-7

C07K 14/705; C07K 16/30; G01N 33/574; A61K 38/17; A61K 39/395; A61P 35/00

IPC 8 full level

G01N 33/50 (2006.01); A61K 31/282 (2006.01); A61K 31/4745 (2006.01); A61K 31/475 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/57 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 31/7068 (2006.01); A61K 33/24 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 16/18 (2006.01); G01N 33/15 (2006.01); G01N 33/574 (2006.01)

CPC (source: EP)

A61P 35/00 (2017.12); C07K 14/705 (2013.01); G01N 33/57484 (2013.01); A61K 2039/505 (2013.01)

Citation (search report)

  • [Y] CHAM B E ET AL: "SOLASODINE GLYCOSIDES. SELECTIVE CYTOTOXICITY FOR CANCER CELLS AND INHIBITION OF CYTOTOXICITY BY RHAMNOSE IN MICE WITH SARCOMA 180", CANCER LETTERS, NEW YORK, NY, US, vol. 55, 1990, pages 221 - 225, XP002950613, ISSN: 0304-3835
  • [Y] CHAM B E ET AL: "TOPICAL TREATMENT OF MALIGNANT AND PREMALIGNANT SKIN LESIONS BY VERY LOW CONCENTRATIONS OF A STANDARD MIXTURE (BEC) OF SOLASODINE GLYCOSIDES", CANCER LETTERS, NEW YORK, NY, US, vol. 59, 1991, pages 183 - 192, XP001077064, ISSN: 0304-3835
  • [A] LIN J-Y ET AL: "ISOLATION OF ANTI TUMOR PROTEINS ABRIN A AND ABRIN B FROM ABRUS-PRECATORIUS", INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, vol. 12, no. 5, 1978, pages 311 - 317, XP009051887, ISSN: 0367-8377
  • [A] NICOLSON G L ET AL: "Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma", BIOCHEMISTRY 1974, vol. 13, no. 1, 1974, pages 196 - 204, XP002339396
  • See references of WO 03066679A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

DOCDB simple family (publication)

WO 03066679 A1 20030814; AU PS036402 A0 20020228; CA 2475066 A1 20030814; CN 1639191 A 20050713; EP 1472287 A1 20041103; EP 1472287 A4 20051005; HK 1080089 A1 20060421; JP 2005538931 A 20051222; NZ 534485 A 20060929

DOCDB simple family (application)

AU 0300135 W 20030207; AU PS036402 A 20020207; CA 2475066 A 20030207; CN 03805513 A 20030207; EP 03700718 A 20030207; HK 06100115 A 20060104; JP 2003566050 A 20030207; NZ 53448503 A 20030207