EP 1473300 B1 20081126 - PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PSORIASIS AND OTHER SKIN DISEASES
Title (en)
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PSORIASIS AND OTHER SKIN DISEASES
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR BEHANDLUNG VON PSORIASIS UND ANDEREN HAUTKRANKHEITEN
Title (fr)
COMPOSITION PHARMACEUTIQUE DESTINEE AU TRAITEMENT DU PSORIASIS ET D'AUTRES PATHOLOGIES CUTANEES
Publication
Application
Priority
- ES 0200591 W 20021211
- ES 200102836 A 20011212
Abstract (en)
[origin: EP1473300A1] The invention relates to a pharmaceutical composition for the treatment of psoriasis and other skin diseases. The inventive composition comprises 17-clobetasol propionate and hydroxy derivative of progesterone having formula (I), wherein: R6 denotes H or methyl; R11 denotes H or hydroxyl and R17 denotes H or hydroxyl, but R11 and R17 cannot be H simultaneously. Preferably, said composition is administered as a lotion with 0.05-0.2 % 17-clobetasol propionate; 0.3-1 % of (I); a solvent selected from among ethanol, isopropanol and mixtures thereof; 40 % cosolvent selected from among propylene glycol, glycerine, sorbitol and mixtures thereof; and 20 % water. In the ideal lotion, the solvent is ethanol and the cosolvents are approximately: 35 % propylene glycol, 5 % glycerine and 20% water. The invention affords the following advantages: longer interval between recurrences and fewer local secondary effects. Moreover, the inventive composition can be used for the treatment of psoriasis. <CHEM>
IPC 8 full level
C07J 7/00 (2006.01); A61K 8/63 (2006.01); A61K 9/00 (2006.01); A61K 31/57 (2006.01); A61K 31/573 (2006.01); A61K 47/10 (2006.01); A61K 47/26 (2006.01); A61P 17/00 (2006.01); A61P 17/06 (2006.01); A61P 29/00 (2006.01); A61P 37/08 (2006.01); A61Q 19/00 (2006.01)
CPC (source: EP ES US)
A61K 8/63 (2013.01 - EP US); A61K 9/0014 (2013.01 - EP US); A61K 31/57 (2013.01 - EP ES US); A61K 31/573 (2013.01 - EP US); A61K 47/10 (2013.01 - EP US); A61P 17/00 (2017.12 - EP); A61P 17/06 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 37/00 (2017.12 - EP); A61P 37/08 (2017.12 - EP); A61Q 19/00 (2013.01 - EP US); C07J 7/00 (2013.01 - EP US); C07J 7/0045 (2013.01 - ES); C07J 7/008 (2013.01 - ES)
C-Set (source: EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
EP 1473300 A1 20041103; EP 1473300 B1 20081126; AT E415410 T1 20081215; AU 2002361265 A1 20030709; CA 2470364 A1 20030703; DE 60230066 D1 20090108; ES 2188426 A1 20030616; ES 2188426 B1 20041116; ES 2318061 T3 20090501; JP 2005513139 A 20050512; PT 1473300 E 20090227; US 2004225140 A1 20041111; WO 03053991 A1 20030703
DOCDB simple family (application)
EP 02796785 A 20021211; AT 02796785 T 20021211; AU 2002361265 A 20021211; CA 2470364 A 20021211; DE 60230066 T 20021211; ES 0200591 W 20021211; ES 02796785 T 20021211; ES 200102836 A 20011212; JP 2003554707 A 20021211; PT 02796785 T 20021211; US 86599104 A 20040611