EP 1476421 A2 20041117 - NOVEL AMINO ACID DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVE
Title (en)
NOVEL AMINO ACID DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVE
Title (de)
AMINOSÄURE-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND SIE ENTHALTENDE ZUSAMMENSETZUNGEN
Title (fr)
NOUVEAUX DERIVES D ACIDES AMINES, LEUR PROCEDE DE PREPARATIO N ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
Publication
Application
Priority
- FR 0300506 W 20030217
- FR 0202199 A 20020221
Abstract (en)
[origin: WO03070690A2] The invention relates to compounds of formula (I): where R1 = an aryl, heteroaryl or alkyl group, optionally substituted with a group of formula -(CO)-CR6R7NR8R9, where R6, R7, R8 and R9 are as defined in the description, R2 = H or optionally substituted alkyl, R3 = H or optionally substituted alkyl, R4 = H or optionally substituted alkyl, or R3 and R4 form, together with the carbon of attachment, an optionally substituted, 3- to 18-membered, saturated or unsaturated mono-, bi- or tri-cyclic system, optionally comprising one or several heteroatoms selected from O, S and N, n = 0, 1 or 2, Ar = aryl or heteroaryl group and R5 = optionally substituted amino, guanidino, cyano or amidino, the optical isomers and addition salts thereof with a pharmacologically acceptable acid. The above are of application as medicaments.
IPC 1-7
C07C 257/18; A61K 31/196; A61P 7/04; C07C 311/13; C07C 311/19; C07D 213/34; C07C 259/18; C07D 295/22; C07D 261/20; C07K 5/06
IPC 8 full level
C07D 295/08 (2006.01); A61K 31/165 (2006.01); A61K 31/18 (2006.01); A61K 31/198 (2006.01); A61K 31/223 (2006.01); A61K 31/27 (2006.01); A61K 31/277 (2006.01); A61K 31/416 (2006.01); A61K 31/423 (2006.01); A61K 31/435 (2006.01); A61K 31/44 (2006.01); A61K 31/4409 (2006.01); A61K 31/5375 (2006.01); A61P 7/04 (2006.01); A61P 43/00 (2006.01); C07C 257/18 (2006.01); C07C 259/18 (2006.01); C07C 303/40 (2006.01); C07C 311/10 (2006.01); C07C 311/13 (2006.01); C07C 311/19 (2006.01); C07D 213/34 (2006.01); C07D 213/68 (2006.01); C07D 213/73 (2006.01); C07D 221/04 (2006.01); C07D 231/56 (2006.01); C07D 261/20 (2006.01); C07D 295/22 (2006.01); C07D 295/26 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP KR US)
A61P 7/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 257/18 (2013.01 - EP KR US); C07C 259/18 (2013.01 - EP KR US); C07C 311/10 (2013.01 - EP US); C07C 311/13 (2013.01 - EP US); C07C 311/19 (2013.01 - EP US); C07D 213/34 (2013.01 - EP US); C07D 261/20 (2013.01 - EP US); C07D 295/26 (2013.01 - EP US); C07K 5/06034 (2013.01 - EP US); C07K 5/06078 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07C 2601/08 (2017.04 - EP US); C07C 2601/14 (2017.04 - EP US); C07C 2602/08 (2017.04 - EP US); C07C 2603/14 (2017.04 - EP US); C07C 2603/28 (2017.04 - EP US)
Citation (search report)
See references of WO 03070690A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03070690 A2 20030828; WO 03070690 A3 20040408; AR 038443 A1 20050112; AU 2003224198 A1 20030909; BR 0307776 A 20041207; CA 2474785 A1 20030828; CN 1257889 C 20060531; CN 1633412 A 20050629; EA 006389 B1 20051229; EA 200401011 A1 20041230; EP 1476421 A2 20041117; FR 2836143 A1 20030822; FR 2836143 B1 20040416; GE P20074100 B 20070510; HK 1079764 A1 20060413; JP 2005517734 A 20050616; JP 4106337 B2 20080625; KR 100668194 B1 20070111; KR 20040085219 A 20041007; MA 27110 A1 20041220; MX PA04007988 A 20041126; NO 20043910 L 20040920; NZ 534359 A 20051223; PL 370817 A1 20050530; UA 77763 C2 20070115; US 2005085517 A1 20050421; US 7265220 B2 20070904; ZA 200406027 B 20060628
DOCDB simple family (application)
FR 0300506 W 20030217; AR P030100563 A 20030221; AU 2003224198 A 20030217; BR 0307776 A 20030217; CA 2474785 A 20030217; CN 03804118 A 20030217; EA 200401011 A 20030217; EP 03720618 A 20030217; FR 0202199 A 20020221; GE AU2003008409 A 20030217; HK 05111846 A 20051222; JP 2003569599 A 20030217; KR 20047013041 A 20030217; MA 27865 A 20040920; MX PA04007988 A 20030217; NO 20043910 A 20040920; NZ 53435903 A 20030217; PL 37081703 A 20030217; UA 20040907682 A 20030217; US 50500504 A 20040818; ZA 200406027 A 20040728