EP 1478758 A1 20041124 - POLYMORPHISMS IN ELASTIN, FIBRILLIN, AND RELATED GENES AS PREDISPOSING TO RESTENOSIS AND TO ATHEROSCLEROSIS
Title (en)
POLYMORPHISMS IN ELASTIN, FIBRILLIN, AND RELATED GENES AS PREDISPOSING TO RESTENOSIS AND TO ATHEROSCLEROSIS
Title (de)
FÜR RESTENOSE UND ATHEROSKLEROSE ANFÄLLIG MACHENDE POLYMORPHISMEN IN ELASTIN-, FIBRILLIN- UND VERWANDTEN GENEN
Title (fr)
POLYMORPHISMES DE GENES D'ELASTINE, DE FIBRILLINE ET DE GENES LIES PREDISPOSANT A UNE RESTENOSE ET A UNE ATHEROSCLEROSE
Publication
Application
Priority
- US 0303001 W 20030203
- US 35288502 P 20020201
Abstract (en)
[origin: WO03064663A1] Methods are provided for assessing the risk of developing restenosis in an individual, by detecting the presence of biologically important polymorphisms in genes involved in the formation of the elastin fiber network. In particular, detection of polymorphorphisms in the elastin, fibrillin, fibrillin-1, fibrillin-2, lysyl oxidase, microfibril-associated glycoprotein, biglycan, osteopontin, and/or decorin genes allows the rapid and objective prediction of the risk of developing restenosis. Methods for treating restenosis and for reducing its recurrence also are provided.
[origin: WO03064663A1] Methods are provided for assessing the risk of developing restenosis in an individual, by detecting the presence of biologically important polymorphisms in genes involved in the formation of the elastin fiber network. In particular, detection of polymorphorphisms in the elastin, fibrillin, fibrillin−1, fibrillin−2, lysyl oxidase, microfibril−associated glycoprotein, biglycan, osteopontin, and/or decorin genes allows the rapid and objective prediction of the risk of developing restenosis. Methods for treating restenosis and for reducing its recurrence also are provided.
IPC 1-7
IPC 8 full level
C12N 15/85 (2006.01); G01N 33/53 (2006.01); A61K 31/7088 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 38/44 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01); C07K 16/18 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 37/00 (2006.01)
CPC (source: EP)
A61P 9/10 (2017.12); A61P 43/00 (2017.12); C12Q 1/6827 (2013.01); C12Q 2600/156 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03064663 A1 20030807; EP 1478758 A1 20041124; EP 1478758 A4 20060830; JP 2005531287 A 20051020
DOCDB simple family (application)
US 0303001 W 20030203; EP 03706019 A 20030203; JP 2003564254 A 20030203