EP 1480648 A4 20071031 - ANTI-VIRAL COMPOUNDS
Title (en)
ANTI-VIRAL COMPOUNDS
Title (de)
ANTIVIRALE VERBINDUNGEN
Title (fr)
COMPOSES ANTIVIRAUX
Publication
Application
Priority
- AU 0300093 W 20030130
- AU PS022802 A 20020131
Abstract (en)
[origin: WO03063869A1] The present invention relates generally to compounds useful in the amelioration of symptoms associated with viral infection. More particularly, the present invention relates to the use of compounds which exhibit a physiological effect on membranous and/or transmembranous structures on or in a cell and which directly or indirectly reduce or inhibit or otherwise prevent viral infection, processing and/or release from the cell. Even more particularly, the present invention contemplates the use of one or more compounds which modulate at least one host cell ion channel in the prophylaxis, treatment and/or symptomatic relief of viral infection in vertebrate animals and in particular in human subjects. The compounds may be provided alone or in combination with other compounds such as those which block or inhibit or at least impair ion channelling. A preferred embodiment of the present invention is the use of the aforementioned anti-viral compounds in the therapeutic management of vertebrate animals including humans, to prevent, reduce or treat infection by certain species of the Picornaviridae family of viral pathogens such as but not limited to Rhinovirus or Enterovirus species.
IPC 1-7
A61K 31/485; A61K 31/52; A61K 38/21; A61K 45/06; A61P 31/12; A61P 31/16
IPC 8 full level
A61K 31/4164 (2006.01); A61K 31/277 (2006.01); A61K 31/485 (2006.01); A61K 31/4965 (2006.01); A61K 31/52 (2006.01); A61K 38/21 (2006.01); A61K 45/06 (2006.01); A61P 31/12 (2006.01); A61P 31/16 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP US)
A61K 31/485 (2013.01 - EP US); A61K 31/52 (2013.01 - EP US); A61K 38/21 (2013.01 - EP US); A61K 45/06 (2013.01 - EP US); A61P 31/12 (2017.12 - EP); A61P 31/16 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
- [X] WO 0128584 A1 20010426 - UNIV SYDNEY [AU], et al
- [X] C HOSLEY ET AL.: "Evidence for poliovirus-induced cytoplasmic alkalinization in HeLa cells", JOURNAL OF CELLULAR PHYSIOLOGY, vol. 142, 1990, pages 586 - 591, XP002452164
- [A] MELNICK ET AL: "The Discovery of the Enteroviruses and the Classification of Poliovirus Among Them", BIOLOGICALS, ACADEMIC PRESS LTD., LONDON, GB, vol. 21, no. 4, December 1993 (1993-12-01), pages 305 - 309, XP022129738, ISSN: 1045-1056
- See references of WO 03063869A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03063869 A1 20030807; AU 2003202298 B2 20070726; AU PS022802 A0 20020221; CA 2474821 A1 20030807; CN 1638772 A 20050713; EP 1480648 A1 20041201; EP 1480648 A4 20071031; JP 2005522425 A 20050728; NZ 534292 A 20080926; US 2005080122 A1 20050414
DOCDB simple family (application)
AU 0300093 W 20030130; AU 2003202298 A 20030130; AU PS022802 A 20020131; CA 2474821 A 20030130; CN 03804954 A 20030130; EP 03700694 A 20030130; JP 2003563559 A 20030130; NZ 53429203 A 20030130; US 50332404 A 20041126