EP 1480682 A1 20041201 - COUPLING PROTEINS TO A MODIFIED POLYSACCHARIDE
Title (en)
COUPLING PROTEINS TO A MODIFIED POLYSACCHARIDE
Title (de)
KOPPLUNG VON PROTEINEN AN EIN MODIFIZIERTES POLYSACCHARID
Title (fr)
COUPLAGE DE PROTEINES AVEC UN POLYSACCHARIDE MODIFIE
Publication
Application
Priority
- DE 10209821 A 20020306
- EP 0302083 W 20030228
Abstract (en)
[origin: WO03074087A1] The invention relates to a method for coupling proteins to a starch-derived modified polysaccharide. The binding interaction between the modified polysaccharide and the protein is based on a covalent bond which is the result of a coupling reaction between the terminal aldehyde group or a functional group of the modified polysaccharide molecule resulting from the chemical reaction of this aldehyde group and a functional group of the protein which reacts with the aldehyde group or with the resulting functional group of the polysaccharide molecule. The bond directly resulting from the coupling reaction can be optionally modified by a further reaction to the aforementioned covalent bond. The invention further relates to pharmaceutical compositions that comprise conjugates formed in this coupling process and to the use of said conjugates and compositions for the prophylaxis or therapy of the human or animal body.
IPC 1-7
IPC 8 full level
A61K 35/58 (2006.01); A61K 35/66 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/21 (2006.01); A61K 38/22 (2006.01); A61K 38/26 (2006.01); A61K 38/27 (2006.01); A61K 38/28 (2006.01); A61K 38/44 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 47/48 (2006.01); A61P 37/02 (2006.01); C07K 1/10 (2006.01); C08B 31/00 (2006.01); C08B 31/18 (2006.01); C08H 1/00 (2006.01); C12N 9/00 (2006.01)
CPC (source: EP KR US)
A61K 38/43 (2013.01 - KR); A61K 47/50 (2017.07 - KR); A61K 47/61 (2017.07 - EP US); A61P 37/02 (2017.12 - EP); C07K 2/00 (2013.01 - KR); C08B 31/00 (2013.01 - EP US); C08B 31/18 (2013.01 - EP KR US); C08B 31/185 (2013.01 - EP US); C08H 1/00 (2013.01 - EP US)
Citation (search report)
See references of WO 03074087A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03074087 A1 20030912; AU 2003215617 A1 20030916; CA 2478478 A1 20030912; CA 2478478 C 20120717; CN 1638808 A 20050713; DE 10209821 A1 20030925; EP 1480682 A1 20041201; IL 163702 A0 20051218; JP 2005528349 A 20050922; KR 20040098001 A 20041118; PL 372481 A1 20050725; US 2005181985 A1 20050818; US 2009233847 A1 20090917; US 7541328 B2 20090602; US 8916518 B2 20141223
DOCDB simple family (application)
EP 0302083 W 20030228; AU 2003215617 A 20030228; CA 2478478 A 20030228; CN 03805183 A 20030228; DE 10209821 A 20020306; EP 03743359 A 20030228; IL 16370203 A 20030228; JP 2003572602 A 20030228; KR 20047013162 A 20030228; PL 37248103 A 20030228; US 47346209 A 20090528; US 50636705 A 20050405