EP 1482940 A2 20041208 - PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
Title (en)
PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
Title (de)
PRODRUGS VON SUBSTITUIERTEN POLYZYCLISCHEN VEBINDUNGEN FÜR DIE SELEKTIVE HEMMUNG DER KOAGULATIONSKASKADE
Title (fr)
PROMEDICAMENTS DE COMPOSES POLYCYCLIQUES SUBSTITUES UTILES POUR L'INHIBITION SELECTIVE DE LA CASCADE DE LA COAGULATION
Publication
Application
Priority
- US 0231468 W 20021003
- US 32672101 P 20011003
- US 33862301 P 20011024
- US 33285701 P 20011106
- US 35005201 P 20011107
- US 34495701 P 20011107
- US 33329201 P 20011114
- US 33210401 P 20011121
- US 33201401 P 20011121
- US 33189101 P 20011121
Abstract (en)
[origin: WO03028729A2] The present invention relates to prodrug compounds, comprising a 5- or 6- membered heterocyclic or aromatic ring substituted with a derivatized amidine, as well as compositions and methods useful for preventing and treating thrombotic conditions in mammals. The prodrug compounds of the present invention selectively inhibit certain proteases of the coagulation cascade.
IPC 1-7
A61K 31/4965; C07D 241/20; C07D 413/12; A61K 31/497; C07D 407/12; C07D 471/04; C07D 401/12
IPC 8 full level
A61K 31/4375 (2006.01); A61K 31/4965 (2006.01); A61K 31/497 (2006.01); A61K 31/4985 (2006.01); A61K 31/536 (2006.01); A61K 31/5377 (2006.01); A61K 45/00 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 43/00 (2006.01); C07C 257/18 (2006.01); C07D 207/32 (2006.01); C07D 211/56 (2006.01); C07D 211/98 (2006.01); C07D 213/74 (2006.01); C07D 231/38 (2006.01); C07D 231/48 (2006.01); C07D 237/04 (2006.01); C07D 239/10 (2006.01); C07D 239/22 (2006.01); C07D 241/04 (2006.01); C07D 241/20 (2006.01); C07D 249/14 (2006.01); C07D 253/06 (2006.01); C07D 253/075 (2006.01); C07D 263/48 (2006.01); C07D 265/02 (2006.01); C07D 277/42 (2006.01); C07D 307/22 (2006.01); C07D 333/36 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 9/00 (2017.12); A61P 11/00 (2017.12); A61P 43/00 (2017.12); C07C 257/18 (2013.01); C07D 207/32 (2013.01); C07D 211/56 (2013.01); C07D 211/98 (2013.01); C07D 213/74 (2013.01); C07D 231/38 (2013.01); C07D 231/48 (2013.01); C07D 237/04 (2013.01); C07D 239/10 (2013.01); C07D 239/22 (2013.01); C07D 241/04 (2013.01); C07D 241/20 (2013.01); C07D 249/14 (2013.01); C07D 253/06 (2013.01); C07D 253/075 (2013.01); C07D 263/48 (2013.01); C07D 265/02 (2013.01); C07D 277/42 (2013.01); C07D 307/22 (2013.01); C07D 333/36 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07C 2601/04 (2017.04); C07C 2601/10 (2017.04)
Citation (search report)
See references of WO 03028729A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 03028729 A2 20030410; WO 03028729 A3 20040916; BR 0213129 A 20040810; CA 2462601 A1 20030410; EP 1482940 A2 20041208; JP 2005509606 A 20050414; MX PA04003169 A 20040708
DOCDB simple family (application)
US 0231468 W 20021003; BR 0213129 A 20021003; CA 2462601 A 20021003; EP 02773700 A 20021003; JP 2003532061 A 20021003; MX PA04003169 A 20021003