Global Patent Index - EP 1487455 A1

EP 1487455 A1 20041222 - MORPHOLINE DERIVATIVES SUBSTITUTED AT THE 2-POSITION BY AN ARYLALKYLUREA GROUP FOR USE AS CCR-3 ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY CONDITIONS

Title (en)

MORPHOLINE DERIVATIVES SUBSTITUTED AT THE 2-POSITION BY AN ARYLALKYLUREA GROUP FOR USE AS CCR-3 ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY CONDITIONS

Title (de)

IN 2-POSITION DURCH EINE ARYLALKYLHARNSTOFF-GRUPPE SUBSTITUIERTE MORPHOLINDERIVATE ZUR VERWENDUNG ALS CCR-3-ANTAGONISTEN BEI DER BEHANDLUNG VON ENTZÜNDLICHEN ERKRANKUNGEN

Title (fr)

DERIVES DE MORPHOLINE SUBSTITUES AU NIVEAU DE LA POSITION 2 PAR UN GROUPE ARYLALKYLUREE UTILISE EN TANT QU'ANTAGONISTES DE CCR-3 DANS LE TRAITEMENT D'ETATS INFLAMMATOIRES

Publication

EP 1487455 A1 20041222 (EN)

Application

EP 03745296 A 20030327

Priority

  • EP 0303340 W 20030327
  • GB 0207436 A 20020328

Abstract (en)

[origin: WO03082292A1] Certain compounds of formula (I); wherein R<1> represents unsubstituted or substituted aryl; Y represents -(CRnaRnb)n-; Rna and Rnb are each independently hydrogen or C1-6 alkyl; n is an integer from 1 to 5; R<2> represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R<3> and R<4> each independently represent hydrogen or C1-6 alkyl; and salts and solvates thereof are CCR3-antagonists and are thus indicated to be useful in therapy of inflammatory conditions.

IPC 1-7

A61K 31/5377; A61K 31/5375; A61P 29/00; A61P 11/06; C07D 265/30; C07D 413/12; C07D 413/06; C07D 209/48

IPC 8 full level

A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61P 11/02 (2006.01); A61P 11/06 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01); C07D 265/30 (2006.01); C07D 413/12 (2006.01)

CPC (source: EP)

A61P 11/02 (2017.12); A61P 11/06 (2017.12); A61P 29/00 (2017.12); A61P 43/00 (2017.12); C07D 265/30 (2013.01); C07D 413/12 (2013.01)

Citation (search report)

See references of WO 03082292A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 03082292 A1 20031009; AR 039172 A1 20050209; AU 2003226759 A1 20031013; EP 1487455 A1 20041222; GB 0207436 D0 20020508; JP 2005526807 A 20050908; TW 200400824 A 20040116

DOCDB simple family (application)

EP 0303340 W 20030327; AR P030101084 A 20030327; AU 2003226759 A 20030327; EP 03745296 A 20030327; GB 0207436 A 20020328; JP 2003579829 A 20030327; TW 92106769 A 20030326