Global Patent Index - EP 1490078 A1

EP 1490078 A1 20041229 - HEPATOCURATIVE EFFECT OF EMBLICA OFFICINALIS ON HEPATOTOXICITY RELATED TO CYTOCHROME P-450

Title (en)

HEPATOCURATIVE EFFECT OF EMBLICA OFFICINALIS ON HEPATOTOXICITY RELATED TO CYTOCHROME P-450

Title (de)

LEBERHEILENDE WIRKUNG VON EMBLICA OFFICINALIS AUF MIT ZYTOCHROM P-450 ZUSAMMENHÄNGENDE LEBERTOXIZITÄT

Title (fr)

EFFET HEPATOCURATIF D'EMBLICA OFFICINALIS SUR L'HEPATOTOXICITE ASSOCIEE AU CYTOCHROME P-450

Publication

EP 1490078 A1 20041229 (EN)

Application

EP 02716955 A 20020326

Priority

IB 0200635 W 20020326

Abstract (en)

[origin: WO03080090A1] The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicity.

IPC 1-7

A61K 35/78

IPC 8 full level

A61K 9/10 (2006.01); A61K 9/12 (2006.01); A61K 9/14 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 36/18 (2006.01); A61K 36/47 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 47/42 (2006.01); A61P 1/16 (2006.01); A61P 39/02 (2006.01); A61P 43/00 (2006.01)

CPC (source: EP KR)

A61K 36/47 (2013.01 - EP KR); A61P 1/16 (2017.12 - EP); A61P 39/02 (2017.12 - EP); A61P 43/00 (2017.12 - EP)

C-Set (source: EP)

A61K 36/47 + A61K 2300/00

Citation (search report)

See references of WO 03080090A1

Citation (examination)

  • DATABASE WPI Section Ch Week 199815, Derwent World Patents Index; Class B04, AN 1998-162497
  • DOTY S.L. ET AL: "Enhanced metabolism of halogenated hydrocarbons in transgenic plants containing mammalian cytochrome P450 2E1", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 97, no. 12, 2000, pages 6287 - 6291
  • YAMAZAKI H. ET AL: "Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009)", CARCINOGENESIS, vol. 13, no. 6, 1992, pages 979 - 985, XP009089415

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

DOCDB simple family (publication)

WO 03080090 A1 20031002; AU 2002247880 A1 20031008; CA 2480334 A1 20031002; CN 1627955 A 20050615; EP 1490078 A1 20041229; JP 2005526792 A 20050908; KR 20040101374 A 20041202

DOCDB simple family (application)

IB 0200635 W 20020326; AU 2002247880 A 20020326; CA 2480334 A 20020326; CN 02829030 A 20020326; EP 02716955 A 20020326; JP 2003577916 A 20020326; KR 20047015457 A 20020326