Global Patent Index - EP 1490348 A1

EP 1490348 A1 20041229 - LABELLED TAXANES

Title (en)

LABELLED TAXANES

Title (de)

MARKIERTE TAXANE

Title (fr)

TAXANES MARQUES

Publication

EP 1490348 A1 20041229 (EN)

Application

EP 03744800 A 20030312

Priority

  • EP 03744800 A 20030312
  • EP 0302634 W 20030312
  • EP 02076113 A 20020321

Abstract (en)

[origin: WO03080587A1] There are provided stable labelled taxanes, characterized in that the isotopes are present in the benzoyloxy group at the C-2 position. More particularly, one or more of the hydrogen or carbon atoms of the benzoyl residue at the C-2 position of the taxane skeleton is replaced respectively from deuterium or 13C.A process for their preparation and their use as internal standard in analytical methods for determining taxanes, useful anticancer drugs, are also provided.

IPC 1-7

C07D 305/14; C07F 7/18; G01N 33/48

IPC 8 full level

G01N 33/50 (2006.01); C07D 305/14 (2006.01); C07F 7/18 (2006.01); G01N 33/48 (2006.01); G01N 33/58 (2006.01)

CPC (source: EP)

C07D 305/14 (2013.01); C07F 7/1804 (2013.01); C07B 2200/05 (2013.01)

Citation (search report)

See references of WO 03080587A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 03080587 A1 20031002; AU 2003227063 A1 20031008; BR 0308612 A 20050209; CA 2479273 A1 20031002; EP 1490348 A1 20041229; JP 2005530715 A 20051013; MX PA04009083 A 20041206

DOCDB simple family (application)

EP 0302634 W 20030312; AU 2003227063 A 20030312; BR 0308612 A 20030312; CA 2479273 A 20030312; EP 03744800 A 20030312; JP 2003578342 A 20030312; MX PA04009083 A 20030312