EP 1490353 A1 20041229 - METHOD FOR MANUFACTURE OF SERTINDOLE
Title (en)
METHOD FOR MANUFACTURE OF SERTINDOLE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON SERTINDOL
Title (fr)
PROCEDE DE FABRICATION DE SERTINDOLE
Publication
Application
Priority
- DK 0300208 W 20030326
- DK PA200200480 A 20020327
- US 36843402 P 20020327
Abstract (en)
[origin: WO03080597A1] The present invention relates to a novel method for manufacture of sertindole comprising manufacturing 5-chloro-1-(4-fluorophenyl)-indole and converting it to sertindole wherein the method for manufacture of 5-chloro-1-(4-fluorophenyl)-indole comprises reacting 5-chloro-indole with a 4-fluorophenylhalide in the presence of a base, a chelating ligand and catalytic amounts of a copper salt comprising copper(I) or copper(II) and an anion which does not interfere in an unfavourable way with the reaction.
IPC 1-7
IPC 8 full level
A61P 25/18 (2006.01); B01J 31/22 (2006.01); C07B 61/00 (2006.01); C07D 209/04 (2006.01); C07D 209/08 (2006.01); C07D 401/14 (2006.01); C07F 1/08 (2006.01)
IPC 8 main group level
C07D (2006.01)
CPC (source: EP KR)
A61P 25/18 (2017.12 - EP); C07D 209/08 (2013.01 - EP KR); C07D 401/14 (2013.01 - EP KR)
Citation (search report)
See references of WO 03080597A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 03080597 A1 20031002; AR 039116 A1 20050209; AU 2003215528 A1 20031008; AU 2003215528 B2 20090528; BR 0308627 A 20050215; CA 2480239 A1 20031002; CA 2480239 C 20101123; CN 100528863 C 20090819; CN 1642942 A 20050720; CO 5611197 A2 20060228; EA 007009 B1 20060630; EA 200401261 A1 20050224; EP 1490353 A1 20041229; EP 1661887 A1 20060531; JP 2005531519 A 20051020; KR 20040095332 A 20041112; ME P6008 A 20100210; NZ 535533 A 20070126; PL 371585 A1 20050627; RS 85004 A 20061215; UA 78300 C2 20070315; ZA 200408273 B 20060726
DOCDB simple family (application)
DK 0300208 W 20030326; AR P030101015 A 20030324; AU 2003215528 A 20030326; BR 0308627 A 20030326; CA 2480239 A 20030326; CN 03807011 A 20030326; CO 04102837 A 20041013; EA 200401261 A 20030326; EP 03744772 A 20030326; EP 05023338 A 20030326; JP 2003578351 A 20030326; KR 20047015339 A 20030326; ME P6008 A 20030326; NZ 53553303 A 20030326; PL 37158503 A 20030326; UA 20041008714 A 20030326; YU P85004 A 20030326; ZA 200408273 A 20041013