EP 1495020 A1 20050112 - N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES
Title (en)
N-(MORPHOLIN-2YL) METHYL ACETAMIDE DERIVATIVES AS CCR-3 ANTAGONISTS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES
Title (de)
N-(MORPHOLIN-2-YL)METHYLACETAMID DERIVATE ALS FÜR DIE BEHANDLUNG VON ENTZÜNDLICHEN ERKRANKUNGEN GEEIGNETE CCR-3-ANTAGONISTEN
Title (fr)
DERIVES DE N-(MORPHOLIN-2YL) METHYLE ACETAMIDE SERVANT D'ANTAGONISTES DE CCR-3 ET UTILISES DANS LE TRAITEMENT DE MALADIES INFLAMMATOIRES
Publication
Application
Priority
- EP 0303350 W 20030327
- GB 0207445 A 20020328
Abstract (en)
[origin: WO03082863A1] Compounds of formula (I); wherein: R<1> represents substituted or unsubstituted heterocyclyl; Y represents -(CRnaRnb)n-; Rna and Rnb are each independently hydrogen or C1-6alkyl; n is an integer from 1 to 5; R<2> represents unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; R<3> represents hydrogen or C1-6alkyl; and salts and solvates thereof are CCR-3 antagonists and are thus indicated to be useful in therapy.
IPC 1-7
C07D 413/12; C07D 241/08; C07D 309/38; A61K 31/5377; A61P 11/06; A61P 17/06; A61P 17/04; A61P 25/28; A61P 37/06; A61P 37/08; A61P 9/10; A61P 1/06; A61P 27/14
IPC 8 full level
A61K 31/5377 (2006.01); A61P 1/06 (2006.01); A61P 9/10 (2006.01); A61P 11/06 (2006.01); A61P 17/04 (2006.01); A61P 17/06 (2006.01); A61P 25/28 (2006.01); A61P 27/14 (2006.01); A61P 27/16 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP)
A61P 1/06 (2017.12); A61P 9/10 (2017.12); A61P 11/06 (2017.12); A61P 17/04 (2017.12); A61P 17/06 (2017.12); A61P 25/28 (2017.12); A61P 27/14 (2017.12); A61P 27/16 (2017.12); A61P 29/00 (2017.12); A61P 37/06 (2017.12); A61P 37/08 (2017.12); C07D 413/12 (2013.01)
Citation (search report)
See references of WO 03082863A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 03082863 A1 20031009; AR 039175 A1 20050209; AU 2003215677 A1 20031013; EP 1495020 A1 20050112; GB 0207445 D0 20020508; JP 2005529094 A 20050929; TW 200403239 A 20040301
DOCDB simple family (application)
EP 0303350 W 20030327; AR P030101088 A 20030327; AU 2003215677 A 20030327; EP 03745300 A 20030327; GB 0207445 A 20020328; JP 2003580328 A 20030327; TW 92106791 A 20030326