Global Patent Index - EP 1501483 A2

EP 1501483 A2 20050202 - PARTICULATE MATERIALS

Title (en)

PARTICULATE MATERIALS

Title (de)

TEILCHENFÖRMIGE MATERIALIEN

Title (fr)

MATERIAUX PARTICULAIRES

Publication

EP 1501483 A2 20050202 (EN)

Application

EP 03747172 A 20030424

Priority

  • GB 0301747 W 20030424
  • GB 0209402 A 20020425
  • GB 0210174 A 20020503
  • GB 0210268 A 20020507
  • GB 0211086 A 20020515
  • GB 0216562 A 20020717

Abstract (en)

[origin: GB2387781A] An active substance in particulate form, methods for preparing them and their uses. Such particulate matter is of use for delivery using a dry powder inhaler (DPI) or similar device and has the following physical properties - (a) a volume mean aerodynamic diameter of less than 7 microns, (b) a density of less than 0.5g/ml and (c) a surface-to-volume ratio of at least twice that of spherical particles of the same volume diameter. The particulate matter is prepared using the solution enhanced dispersion by supercritical fluid technique (SEDS<TM>). The matter produced when delivered using a passive dry powder inhaler yields a fine particle fraction in the emitted dose which is at least 20% greater than that of the same active substance produced by micronisation, granulation or solvent crystallisation and having the same or smaller mean diameter. The active substances of particular interest include salbutamol, terbutaline, salmeterol, fenoterol and brornocriptine.

IPC 1-7

A61K 9/14; A61K 9/72

IPC 8 full level

A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61P 11/00 (2006.01)

CPC (source: EP)

A61K 9/0075 (2013.01); A61K 9/1688 (2013.01); A61P 11/00 (2017.12); A61K 9/0043 (2013.01)

Citation (search report)

See references of WO 03090715A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

GB 2387781 A 20031029; GB 2387781 A8 20031217; AU 2003226567 A1 20031110; CA 2483218 A1 20031106; CA 2483218 C 20120710; EP 1501483 A2 20050202; WO 03090715 A2 20031106; WO 03090715 A3 20040311

DOCDB simple family (application)

GB 0309295 A 20030424; AU 2003226567 A 20030424; CA 2483218 A 20030424; EP 03747172 A 20030424; GB 0301747 W 20030424