EP 1501535 A1 20050202 - ANTAGONISTS OF MEGALIN OR CUBILIN FOR USE IN PREVENTING ORGAN DAMAGE INDUCED BY THERAPEUTIC AGENTS
Title (en)
ANTAGONISTS OF MEGALIN OR CUBILIN FOR USE IN PREVENTING ORGAN DAMAGE INDUCED BY THERAPEUTIC AGENTS
Title (de)
ANTAGONISTEN VON MEGALIN ODER CUBILIN ZUR VERWENDUNG BEI DER PRÄVENTION VON DURCH THERAPEUTISCHE MITTEL AUSGELÖSTEN ORGANSCHÄDEN
Title (fr)
ANTAGONISTES DE MEGALINE OU DE CUBILINE DESTINES A ETRE UTILISES DANS LA PREVENTION DE L'ENDOMMAGEMENT D'ORGANES INDUIT PAR DES AGENTS THERAPEUTIQUES
Publication
Application
Priority
IB 0201393 W 20020425
Abstract (en)
[origin: WO03080103A1] The invention relates to agents for the prevention of organ damage, in particular of the kidneys and the inner ear, induced by the administration of aminoglycosides. Agents according to the invention are all substances which are megalin and/or cubilin antagonists (inhibitors). In particular, these are molecules (compounds) having polybasic structures which bind to megalin and inhibit the binding of aminoglyco-sides and related substances.
IPC 1-7
IPC 8 full level
A61K 31/19 (2006.01); A61K 31/519 (2006.01); A61K 31/535 (2006.01); A61K 31/7036 (2006.01); A61K 31/7048 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/57 (2006.01); A61K 45/06 (2006.01); A61P 13/12 (2006.01)
CPC (source: EP)
A61K 31/19 (2013.01); A61K 31/519 (2013.01); A61K 31/535 (2013.01); A61K 31/7036 (2013.01); A61K 31/7048 (2013.01); A61K 38/12 (2013.01); A61K 38/177 (2013.01); A61K 38/57 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2017.12); A61K 2039/505 (2013.01)
Citation (search report)
See references of WO 03080103A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 03080103 A1 20031002; WO 03080103 A8 20040108; AU 2002307802 A1 20031008; AU 2002307802 A8 20031008; EP 1501535 A1 20050202
DOCDB simple family (application)
IB 0201393 W 20020425; AU 2002307802 A 20020425; EP 02807105 A 20020425