EP 1503806 A1 20050209 - METHOD FOR PREVENTING DAMAGE TO OR REJUVENATING A CELLULAR BLOOD COMPONENT USING MITOCHONDRIAL ENHANCER
Title (en)
METHOD FOR PREVENTING DAMAGE TO OR REJUVENATING A CELLULAR BLOOD COMPONENT USING MITOCHONDRIAL ENHANCER
Title (de)
VERFAHREN ZUR PRÄVENTION VON BESCHÄDIGUNG AN ODER ZUR VERJÜNGUNG VON EINER ZELLULÄREN BLUTKOMPONENTE DURCH MITOCHONDRIENVERSTÄRKER
Title (fr)
PROCEDE PERMETTANT D'EVITER L'ENDOMMAGEMENT OU D'ASSURER LE RAJEUNISSEMENT D'UN COMPOSANT SANGUIN CELLULAIRE A L'AIDE D'UN AMPLIFICATEUR MITOCHONDRIAL
Publication
Application
Priority
- US 0314070 W 20030506
- US 37837402 P 20020506
Abstract (en)
[origin: WO03094979A1] This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and rejuvenate mitochondria and cells containing mitochondria. Mitochondrial enhancers include alloxazines and related compounds, such as riboflavin. Cells are optionally treated with photoradiation to reduce pathogens with may be present, before, after, and/or during treatment with mitochondrial enhancer. Treating with mitochondrial enhancer enables utilization of higher photoradiation energies, which achieves better pathogen reduction. When platelets are treated with mitochondrial enhancer, treated platelets may be stored for longer times than untreated platelets before they are administered to patients.
IPC 1-7
A61L 2/00; A61L 2/08; A61L 2/18; A61K 31/525; A61K 35/14; A61K 41/00; A61M 1/36; C12N 7/04
IPC 8 full level
A61L 2/10 (2006.01); A61K 31/525 (2006.01); A61K 35/14 (2006.01); A61K 35/19 (2015.01); A61K 41/00 (2006.01); A61L 2/00 (2006.01)
CPC (source: EP)
A61K 31/525 (2013.01); A61K 35/19 (2013.01); A61K 41/17 (2020.01); A61L 2/0005 (2013.01); A61L 2/0011 (2013.01); A61L 2/0082 (2013.01); A61M 2202/0413 (2013.01)
Citation (search report)
See references of WO 03094979A1
Designated contracting state (EPC)
DE FR GB IT
DOCDB simple family (publication)
WO 03094979 A1 20031120; AU 2003241366 A1 20031111; CA 2483046 A1 20031120; EP 1503806 A1 20050209; JP 2005524714 A 20050818
DOCDB simple family (application)
US 0314070 W 20030506; AU 2003241366 A 20030506; CA 2483046 A 20030506; EP 03731098 A 20030506; JP 2004503062 A 20030506