EP 1503978 A1 20050209 - PROCESS FOR THE MANUFACTURE OF SERTRALINE
Title (en)
PROCESS FOR THE MANUFACTURE OF SERTRALINE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON SERTRALIN
Title (fr)
PROCEDE DE FABRICATION DE SERTRALINE
Publication
Application
Priority
CZ 0200028 W 20020510
Abstract (en)
[origin: WO03099761A1] Process for the preparation of sertraline by reductive amination of racemic 4-(3, 4-dichlorophenyl)-3, 4-dihydro-1-(2H)-naphthalenone, carried out as one- reaction-vessel process without isolation of intermediates, in the form of pure separated cis and trans isomers, the way of conversion of trans isomer to cis isomer and preparation of FII polymorph of 1S-cis isomer from any other polymorph.
IPC 1-7
IPC 8 full level
C07C 209/24 (2006.01)
CPC (source: EP)
C07C 209/28 (2013.01); C07C 2602/10 (2017.05)
C-Set (source: EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 03099761 A1 20031204; AU 2002311059 A1 20031212; CA 2485499 A1 20031204; EP 1503978 A1 20050209; HU P0500215 A2 20050628
DOCDB simple family (application)
CZ 0200028 W 20020510; AU 2002311059 A 20020510; CA 2485499 A 20020510; EP 02734991 A 20020510; HU P0500215 A 20020510