Global Patent Index - EP 1503979 B9

EP 1503979 B9 20141029 - PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS

Title (en)

PROCESS FOR HYDROGENATING UNACTIVATED IMINES USING RUTHENIUM COMPLEXES AS CATALYSTS

Title (de)

PROZESS ZUR HYDRIERUNG VON NICHT-AKTIVIERTEN IMINEN UNTER VERWENDUNG VON RUTHENIUM-KOMPLEXEN ALS KATALYSATOREN

Title (fr)

PROCEDE D'HYDROGENATION D'IMINES INACTIVEES A L'AIDE DE COMPLEXES DE RUTHENIUM UTILISES COMME CATALYSEURS

Publication

EP 1503979 B9 20141029 (EN)

Application

EP 03720057 A 20030515

Priority

  • CA 0300689 W 20030515
  • US 38025602 P 20020515

Abstract (en)

[origin: WO03097571A1] A process is provided for the hydrogenation or asymmetric hydrogenation of dialkyl, alkylalkenyl and dialkenyl imines of formula (II) to provide amines of formula (III), wherein, (i) R<1> and R<2> are optionally substituted cyclic, linear or branched alkyl or alkenyl; R<3> is a hydrogen atom, a hydroxy radical, optionally substituted C1 to C8 cyclic, linear or branched alkyl or alkenyl, optionally substituted aryl; or (ii) R<1> is alkyl or alkenyl, R<2> is alkyl or alkenyl and the two are linked together or with R<3> to form one or more rings; using a catalytic system comprising a base and a ruthenium complex containing (1) a diamine and (2) a diphosphine ligand or monodentate phosphine ligands in hydrogenation and asymmetric hydrogenation processes.

IPC 8 full level

C07C 209/52 (2006.01); C07D 487/08 (2006.01); B01J 31/24 (2006.01); C07B 53/00 (2006.01); C07B 61/00 (2006.01); C07C 211/48 (2006.01)

CPC (source: EP)

C07C 209/52 (2013.01); C07D 453/02 (2013.01); C07B 2200/07 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05)

C-Set (source: EP)

  1. C07C 209/52 + C07C 211/48
  2. C07C 209/52 + C07C 211/42

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 03097571 A1 20031127; AT 496880 T 20110215; AU 2003223806 A1 20031202; AU 2003223806 B2 20090108; CA 2489158 A1 20031127; CA 2489158 C 20100803; DE 60335874 D1 20110310; EP 1503979 A1 20050209; EP 1503979 B1 20110126; EP 1503979 B9 20141029; IL 164915 A 20101230; IL 164915 D0 20051218; JP 2005525426 A 20050825; US 2005209487 A1 20050922; US 7256311 B2 20070814

DOCDB simple family (application)

CA 0300689 W 20030515; AT 03720057 T 20030515; AU 2003223806 A 20030515; CA 2489158 A 20030515; DE 60335874 T 20030515; EP 03720057 A 20030515; IL 16491504 A 20041028; JP 2004505305 A 20030515; US 51332105 A 20050601