Global Patent Index - EP 1507777 A2

EP 1507777 A2 20050223 - PROCESS FOR PREPARING CRYSTALLINE FORM I OF CABERGOLINE

Title (en)

PROCESS FOR PREPARING CRYSTALLINE FORM I OF CABERGOLINE

Title (de)

VERFAHREN ZUR HERSTELLUNG DER KRISTALLFORM I VON CABERGOLIN

Title (fr)

PROCEDE DE PREPARATION D'UNE FORME I CRISTALLINE DE CABERGOLINE

Publication

EP 1507777 A2 20050223 (EN)

Application

EP 03721346 A 20030310

Priority

  • US 0307138 W 20030310
  • US 36456702 P 20020315
  • US 41025302 P 20020912

Abstract (en)

[origin: WO03078392A2] A process for producing crystalline form I of cabergoline, which process comprises crystallization of the desired form from a toluene/heptane or toluene/hexane mixture starting from raw cabergoline, followed by recovery and removal of the solvent from the resulting toluene solvate Form X. The new solvate Form X of cabergoline, useful intermediate, and its preparation are also provided.

IPC 1-7

C07D 457/04; C07D 457/06

IPC 8 full level

C07D 457/06 (2006.01); C07D 471/04 (2006.01); C07D 261/08 (2006.01)

CPC (source: EP KR)

C07D 457/04 (2013.01 - KR); C07D 457/06 (2013.01 - EP KR)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

Designated extension state (EPC)

AL LT LV MK

DOCDB simple family (publication)

WO 03078392 A2 20030925; WO 03078392 A3 20031211; AU 2003224665 A1 20030929; BR 0308472 A 20050111; CA 2478149 A1 20030925; CN 1642953 A 20050720; EP 1507777 A2 20050223; EP 1507777 A4 20070307; IL 163779 A0 20051218; JP 2005520831 A 20050714; KR 100605794 B1 20060801; KR 20050002858 A 20050110; MX PA04008935 A 20041126; PL 372371 A1 20050725; RS 77704 A 20061027; RU 2004127582 A 20060127; RU 2277536 C2 20060610; TW 200306312 A 20031116

DOCDB simple family (application)

US 0307138 W 20030310; AU 2003224665 A 20030310; BR 0308472 A 20030310; CA 2478149 A 20030310; CN 03806130 A 20030310; EP 03721346 A 20030310; IL 16377903 A 20030310; JP 2003576398 A 20030310; KR 20047014429 A 20030310; MX PA04008935 A 20030310; PL 37237103 A 20030310; RU 2004127582 A 20030310; TW 92105467 A 20030313; YU P77704 A 20030310