EP 1512013 A2 20050309 - DIAGNOSTIC AND THERAPEUTIC USE OF STEROIDOGENIC ACUTE REGULATORY PROTEIN FOR NEURODEGENERATIVE DISEASES
Title (en)
DIAGNOSTIC AND THERAPEUTIC USE OF STEROIDOGENIC ACUTE REGULATORY PROTEIN FOR NEURODEGENERATIVE DISEASES
Title (de)
DIAGNOSTISCHE UND THERAPEUTISCHE VERWENDUNG DES STEROIDOGENEN AKUT REGULATORISCHEN PROTEINS (STAR) FÜR NEURODEGENERATIVE ERKRANKUNGEN
Title (fr)
UTILISATION DIAGNOSTIQUE ET THERAPEUTIQUE DE LA PROTEINE REGULATRICE DE REPONSE STEROIDOGENE AIGUE POUR TRAITER DES MALADIES NEURODEGENERATIVES
Publication
Application
Priority
- EP 03730155 A 20030605
- EP 0305910 W 20030605
- EP 02012815 A 20020610
- US 38672102 P 20020610
Abstract (en)
[origin: WO03104811A2] The present invention discloses the differential expression of the steroidogenic acute regulatory protein (StAR) gene in specific brain regions of Alzheimer's disease patients. Based on this finding, this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using the StAR gene and gene products. A method of screening for modulating agents of neurodegenerative diseases is also disclosed.
IPC 1-7
G01N 33/68; A61P 25/28; A01K 67/027; C12N 15/00; C07K 14/705
IPC 8 full level
A01K 67/027 (2006.01); A61P 25/28 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 21/78 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 25/28 (2017.12); C07K 14/4711 (2013.01); G01N 33/6896 (2013.01); A01K 2217/05 (2013.01); G01N 2500/00 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2821 (2013.01)
Citation (search report)
See references of WO 03104811A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 03104811 A2 20031218; WO 03104811 A3 20041014; AU 2003240746 A1 20031222; AU 2003240746 A8 20031222; EP 1512013 A2 20050309; JP 2005531305 A 20051020
DOCDB simple family (application)
EP 0305910 W 20030605; AU 2003240746 A 20030605; EP 03730155 A 20030605; JP 2004511831 A 20030605