EP 1516189 A2 20050323 - DIAGNOSTIC AND THERAPEUTIC USE OF ENSADIN-0581 GENE AND PROTEIN FOR NEURODEGENERATIVE DISEASES
Title (en)
DIAGNOSTIC AND THERAPEUTIC USE OF ENSADIN-0581 GENE AND PROTEIN FOR NEURODEGENERATIVE DISEASES
Title (de)
DIAGNOSTISCHE UND THERAPEUTISCHE VERWENDUNG VON ENSADIN-0581 GEN UND PROTEIN FÜR NEURODEGENERATIVE ERKRANKUNGEN
Title (fr)
UTILISATION DIAGNOSTIQUE ET THERAPEUTIQUE DE LA PROTEINE ET DU GENE ENSADIN-0581 DANS LE CADRE DES MALADIES NEURODEGENERATIVES
Publication
Application
Priority
- EP 03761509 A 20030626
- EP 0306719 W 20030626
- EP 02014313 A 20020627
- US 39161402 P 20020627
Abstract (en)
[origin: WO2004003563A2] The present invention discloses the differential expression of a gene coding for Ensadin-0581 in specific brain regions of Alzheimer's disease patients. Based on this finding, this invention provides a method for diagnosing or prognosticating a neurodegenerative disease, in particular Alzheimer's disease, in a subject, or for determining whether a subject is at increased risk of developing such a disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using the Ensadin-0581 gene and its corresponding gene products. A method of screening for modulating agents of neurodegenerative diseases is also disclosed.
IPC 1-7
IPC 8 full level
C07K 14/47 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
C07K 14/4711 (2013.01); G01N 33/6896 (2013.01); A01K 2217/05 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2821 (2013.01)
Citation (search report)
See references of WO 2004003563A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004003563 A2 20040108; WO 2004003563 A3 20040304; AU 2003260301 A1 20040119; AU 2003260301 A8 20040119; DE 60317671 D1 20080103; DE 60317671 T2 20081030; EP 1516189 A2 20050323; EP 1516189 B1 20071121
DOCDB simple family (application)
EP 0306719 W 20030626; AU 2003260301 A 20030626; DE 60317671 T 20030626; EP 03761509 A 20030626