EP 1517685 A1 20050330 - 2-(PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID-N-4-(THIOXO-HETEROCYCLYL)-PHENYL-AMIDE DERIVATIVES AND CORRESPONDING IMINO-HETEROCYCLYL DERIVATIVES AND RELATES COMPOUNDS FOR USE AS INHIBITORS OF THE COAGULATION FACTORS XA AND/OR VIIA FOR TREATING THROMBOSES
Title (en)
2-(PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID-N-4-(THIOXO-HETEROCYCLYL)-PHENYL-AMIDE DERIVATIVES AND CORRESPONDING IMINO-HETEROCYCLYL DERIVATIVES AND RELATES COMPOUNDS FOR USE AS INHIBITORS OF THE COAGULATION FACTORS XA AND/OR VIIA FOR TREATING THROMBOSES
Title (de)
2-(PHENYL)-2H-PYRAZOL-3-CARBONSÄURE-N-4-(THIOXO-HETEROCYCLYL)-PHENYL-AMID DERIVATE UND ENTSPRECHENDE IMINO-HETEROCYCLYL DERIVATE SOWIE VERWANDTE VERBINDUNGEN ALS INHIBITOREN DER KOAGULATIONSFAKTOREN XA UND/ODER VIIA ZUR BEHANDLUNG VON THROMBOSEN
Title (fr)
DERIVES DE 2-(PHENYL)-2H-PYRAZOL-3-ACIDE CARBOXYLIQUE-N-4-(THIOXO-HETEROCYCLYL)-PHENYL-AMIDE, DERIVES D IMINO-HETEROCYCLYLE C ORRESPONDANTS ET COMPOSES DERIVES SERVANT D INHIBITEURS DES FACTEURS DE COAGULATION XA ET/OU VIIA DANS LE TRAITEMENT DE THROMBOSES
Publication
Application
Priority
- DE 10229070 A 20020628
- EP 0305898 W 20030605
Abstract (en)
[origin: WO2004002477A1] The invention relates to the novel compounds of formula (I), wherein D, M, W, X, Y, T, R<1> and R<1'> are defined as in patent claim 1. The inventive compounds are inhibitors of coagulation factor Xa and can be used in the prophylaxis and/or therapy of thromboembolic diseases and in the treatment of tumors.
IPC 1-7
A61K 31/4155; A61K 31/4178; A61K 31/433; A61K 31/42; C07D 403/12; C07D 417/12; C07D 413/14; C07D 403/14
IPC 8 full level
A61K 31/4155 (2006.01); A61K 31/4178 (2006.01); A61K 31/42 (2006.01); A61K 31/433 (2006.01); A61P 7/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 25/06 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01)
CPC (source: EP US)
A61K 31/4155 (2013.01 - EP US); A61K 31/4178 (2013.01 - EP US); A61K 31/42 (2013.01 - EP US); A61K 31/433 (2013.01 - EP US); A61P 7/02 (2017.12 - EP); A61P 9/08 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 35/04 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 403/12 (2013.01 - EP US); C07D 403/14 (2013.01 - EP US); C07D 413/14 (2013.01 - EP US); C07D 417/12 (2013.01 - EP US); Y02P 20/55 (2015.11 - EP US)
Citation (search report)
See references of WO 2004002477A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004002477 A1 20040108; WO 2004002477 A8 20040415; AR 040472 A1 20050406; AU 2003238475 A1 20040119; CA 2491271 A1 20040108; DE 10229070 A1 20040115; EP 1517685 A1 20050330; EP 1679073 A1 20060712; JP 2005535630 A 20051124; US 2005203127 A1 20050915
DOCDB simple family (application)
EP 0305898 W 20030605; AR P030102321 A 20030627; AU 2003238475 A 20030605; CA 2491271 A 20030605; DE 10229070 A 20020628; EP 03732540 A 20030605; EP 06000157 A 20030605; JP 2004516575 A 20030605; US 51935604 A 20041228