Global Patent Index - EP 1517997 A2

EP 1517997 A2 20050330 - LUMINOGENIC PROTEASE SUBSTRATES

Title (en)

LUMINOGENIC PROTEASE SUBSTRATES

Title (de)

LUMINOGENE PROTEASESUBSTRATE

Title (fr)

SUBSTRATS LUMINOGENES POUR PROTEASES

Publication

EP 1517997 A2 20050330 (EN)

Application

EP 03729139 A 20030523

Priority

  • US 0316530 W 20030523
  • US 38336302 P 20020524

Abstract (en)

[origin: WO03099780A2] Systems, including compositions, kits, and methods, suitable for performing enzyme assays, such as protease assays. The composition may include derivatives of rhodamine 110 that are substitued at the xanthylium nitrogens by a peptide moiety and a morpholine-4-carbonyl moiety, respectively. These compositions may be luminogenic substrates for a large variety of protease enzymes, with utility in a variety of sensitive protease enzyme assays.

IPC 1-7

C12Q 1/37; G01N 33/50; A61K 38/06; A61K 38/07; C09K 11/06; C07D 311/88

IPC 8 full level

C07D 311/82 (2006.01); C07D 493/10 (2006.01); C07K 5/02 (2006.01); C07K 7/02 (2006.01); C12Q 1/37 (2006.01)

CPC (source: EP)

C07D 311/82 (2013.01); C07D 493/10 (2013.01); C07K 5/021 (2013.01); C07K 7/02 (2013.01); C12Q 1/37 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 03099780 A2 20031204; WO 03099780 A3 20040401; AU 2003234638 A1 20031212; AU 2003234638 A8 20031212; EP 1517997 A2 20050330; EP 1517997 A4 20061115

DOCDB simple family (application)

US 0316530 W 20030523; AU 2003234638 A 20030523; EP 03729139 A 20030523