EP 1519930 B1 20101020 - BENZOPROSTACYCLIN INTERMEDIATES AND METHODS FOR THEIR PREPARATION
Title (en)
BENZOPROSTACYCLIN INTERMEDIATES AND METHODS FOR THEIR PREPARATION
Title (de)
BENZOPROSTACYCLINZWISCHENPRODUKTE UND VERFAHREN ZU DEREN HERSTELLUNG
Title (fr)
INTERMEDIAIRES DE BENZOPROSTACYCLINE ET PROCEDES DE PREPARATION DE CES INTERMEDIAIRES
Publication
Application
Priority
- GB 0302924 W 20030708
- GB 0215757 A 20020708
Abstract (en)
[origin: WO2004005274A1] Benzoprostacyclin intermediates and methods for their preparation are disclosed. The intermediates may be used to synthesise Beraprost which is a valuable drug for the treatment of pulmonary vascular and peripheral vascular diseases. The intermediates are synthesised via a convergent seven step approach based on the known racemic cyclopentenone intermediate (±)-2-(2-allyloxy-3-bromophenyl)-4-hydroxy-cyclopent-2-enone (1).
IPC 8 full level
C07D 307/93 (2006.01); C07B 61/00 (2006.01); C07F 7/18 (2006.01)
CPC (source: EP)
C07D 307/93 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004005274 A1 20040115; AT E485285 T1 20101115; AU 2003250392 A1 20040123; DE 60334620 D1 20101202; EP 1519930 A1 20050406; EP 1519930 B1 20101020; GB 0215757 D0 20020814; JP 2005538976 A 20051222; JP 5259045 B2 20130807
DOCDB simple family (application)
GB 0302924 W 20030708; AT 03762807 T 20030708; AU 2003250392 A 20030708; DE 60334620 T 20030708; EP 03762807 A 20030708; GB 0215757 A 20020708; JP 2004518990 A 20030708